Mechanisms and clinical implications of endothelium-dependent vasomotor dysfunction in coronary microvasculature
Coronary microvascular disease (CMD), which affects the arterioles and capillary
endothelium that regulate myocardial perfusion, is an increasingly recognized source of …
endothelium that regulate myocardial perfusion, is an increasingly recognized source of …
Endothelial dysfunction: clinical implications
H Drexler - Progress in cardiovascular diseases, 1997 - Elsevier
The endothelium is involved in the control of vascular tone and homeostasis. Risk factors for
arteriosclerosis, as well as other conditions have been shown to be associated with a …
arteriosclerosis, as well as other conditions have been shown to be associated with a …
Coronary hemodynamic and metabolic studies of the coronary slow flow phenomenon
JF Beltrame, SB Limaye, RD Wuttke, JD Horowitz - American heart journal, 2003 - Elsevier
BACKGROUND: The coronary slow flow phenomenon (CSFP) is an angiographic finding
characterized by Thrombolysis in Myocardial Infarction (TIMI)-2 flow in the absence of …
characterized by Thrombolysis in Myocardial Infarction (TIMI)-2 flow in the absence of …
Postischemic vasodilation in human forearm is dependent on endothelium-derived nitric oxide
IT Meredith, KE Currie, TJ Anderson… - American Journal …, 1996 - journals.physiology.org
Although endothelium-derived nitric oxide contributes to basal vascular tone, little is known
about its role in regulating blood flow during changes in metabolic supply and demand. We …
about its role in regulating blood flow during changes in metabolic supply and demand. We …
Role of adenosine in pathogenesis of anginal pain.
The intravenous infusion of adenosine provokes anginalike chest pain. To establish its
origin, an intracoronary infusion of increasing adenosine concentrations was given in 22 …
origin, an intracoronary infusion of increasing adenosine concentrations was given in 22 …
Effect of inhibition of nitric oxide synthesis on epicardial coronary artery caliber and coronary blood flow in humans.
BACKGROUND NG-Monomethyl-L-arginine (L-NMMA), a specific inhibitor of nitric oxide
synthesis, was used to determine the effects of inhibition of nitric oxide synthesis in the …
synthesis, was used to determine the effects of inhibition of nitric oxide synthesis in the …
[图书][B] Endothelial and neuro-humoral control of coronary blood flow in health and disease
E Bassenge, G Heusch - 1990 - Springer
Several reviews of coronary physiology have been published in the last decade (Bassenge
1984; Berne and Rubio 1979; Feigl 1983). The purpose of the present review is to provide …
1984; Berne and Rubio 1979; Feigl 1983). The purpose of the present review is to provide …
[HTML][HTML] Delayed recovery of coronary resistive vessel function after coronary angioplasty
Objectives. The aim of this study was to use Doppler catheterization and sequential dynamic
positron emission tomography (PET) to investigate the role and time course of abnormal …
positron emission tomography (PET) to investigate the role and time course of abnormal …
Effects of neuronal nitric oxide synthase on human coronary artery diameter and blood flow in vivo
M Seddon, N Melikian, R Dworakowski, H Shabeeh… - Circulation, 2009 - Am Heart Assoc
Background—Nitric oxide (NO)–mediated local regulation of vascular tone is considered to
involve endothelial NO synthase (eNOS). However, we recently reported that human …
involve endothelial NO synthase (eNOS). However, we recently reported that human …
Low basal and stimulated release of nitric oxide in atherosclerotic epicardial coronary arteries
AH Chester, GS O'neil, S Tadjkarimi, MH Yacoub… - The Lancet, 1990 - Elsevier
Endothelium-dependent relaxations in response to substance P and bradykinin were lower
in atherosclerotic than in normal human coronary arteries. The relaxation induced by …
in atherosclerotic than in normal human coronary arteries. The relaxation induced by …