Resistant and refractory migraine: clinical presentation, pathophysiology, and management

R Ornello, AP Andreou, E De Matteis, TP Jürgens… - …, 2024 - thelancet.com
Migraine is a leading cause of disability worldwide. A minority of individuals with migraine
develop resistant or refractory conditions characterised by≥ 8 monthly days of debilitating …

Eptinezumab for the Prevention of Migraine: clinical utility, patient preferences and selection–a narrative review

C Altamura, N Brunelli, M Marcosano… - … and Clinical Risk …, 2023 - Taylor & Francis
Abstract The new Calcitonin Gene-Related Peptide (CGRP)-targeted therapies have proven
high efficacy and tolerability in episodic and chronic migraine. Eptinezumab is a humanized …

Prevalence and risk factors of De Novo widespread Post-COVID Pain in Nonhospitalized COVID-19 survivors: a nationwide exploratory Population-based survey

BD Ebbesen, R Giordano, JA Valera-Calero… - The Journal of …, 2024 - Elsevier
This survey investigated the prevalence of de novo widespread musculoskeletal post-
COVID pain and risk factors for its development in nonhospitalized COVID-19 survivors. A …

Breaking the cycle: unraveling the diagnostic, pathophysiological and treatment challenges of refractory migraine

J Robblee - Frontiers in Neurology, 2023 - frontiersin.org
Background Refractory migraine is a poorly described complication of migraine in which
migraine has chronified and become resistant to standard treatments. The true prevalence is …

Alleviation of migraine related pain and anxiety by inhibiting calcium-stimulating AC1-dependent CGRP in the insula of adult rats

Y Li, C Li, QY Chen, S Hao, J Mao, W Zhang… - The Journal of …, 2024 - Springer
Background Recent animal and clinical findings consistently highlight the critical role of
calcitonin gene-related peptide (CGRP) in chronic migraine (CM) and related emotional …

Does pain self-efficacy predict, moderate or mediate outcomes in people with chronic headache; an exploratory analysis of the CHESS trial

SW Hee, S Patel, H Sandhu, MS Matharu… - The Journal of …, 2024 - Springer
Background Chronic headache disorders are disabling. The CHESS trial studied the effects
of a short non-pharmacological intervention of education with self-management support for …

[HTML][HTML] Efficacy of Desvenlafaxine in Reducing Migraine Frequency and Severity: A Retrospective Study

M Stoupa Hadidi, M Rasheed, YM Bisharat… - Journal of Clinical …, 2024 - mdpi.com
Background: Migraine is characterized by sudden acute episodes of pain, with a global
prevalence of 18% among all age groups. It is the second leading cause of years lived with …

[HTML][HTML] Pain from Internal Organs and Headache: The Challenge of Comorbidity

G Affaitati, R Costantini, M Fiordaliso… - Diagnostics, 2024 - mdpi.com
Headache and visceral pain are common clinical painful conditions, which often co-exist in
the same patients. Numbers relative to their co-occurrence suggest possible common …

Migräne und psychosomatische Komorbiditäten

R Ruscheweyh, N Lehnen… - Fortschritte der …, 2024 - thieme-connect.com
Die Migräne als häufige neurologische Erkrankung (10-15% der Bevölkerung) ist mit
zahlreichen Komorbiditäten assoziiert, insbesondere mit anderen Schmerzsyndromen …

Headache, Migraines, Obesity and Medication Burden on Fibromyalgia Impact and Quality of Life

Y Abdullah, R Aziz, MMO Diaz, L Yu… - Medical Research …, 2024 - esmed.org
Fibromyalgia (FM) is a common, complex, and chronic pain disorder characterized by
widespread musculoskeletal pain, fatigue, and tenderness in localized areas. A multitude of …