HIF-1α/Ascl2/miR-200b regulatory feedback circuit modulated the epithelial-mesenchymal transition (EMT) in colorectal cancer cells
Y Shang, H Chen, J Ye, X Wei, S Liu, R Wang - Experimental cell research, 2017 - Elsevier
We have reported that Achaete scute-like 2 (Ascl2) transcriptionally repressed miR-200
family members and affected the epithelial-mesenchymal transition (EMT)-mesenchymal …
family members and affected the epithelial-mesenchymal transition (EMT)-mesenchymal …
miRNA networks modulate human endothelial cell adaptation to cyclic hypoxia
K Kochan-Jamrozy, J Króliczewski, A Moszyńska… - Cellular signalling, 2019 - Elsevier
Solid tumor microenvironments are often subjected to various levels of hypoxia. Although
regulation of gene expression has been examined extensively, most studies have focused …
regulation of gene expression has been examined extensively, most studies have focused …
miR‐200a/b/‐429 downregulation is a candidate biomarker of tumor radioresistance and independent of hypoxia in locally advanced cervical cancer
A Nilsen, T Hillestad, VE Skingen… - Molecular …, 2022 - Wiley Online Library
Many patients with locally advanced cervical cancer experience recurrence within the
radiation field after chemoradiotherapy. Biomarkers of tumor radioresistance are required to …
radiation field after chemoradiotherapy. Biomarkers of tumor radioresistance are required to …
Novel cancer treatment paradigm targeting hypoxia-induced factor in conjunction with current therapies to overcome resistance
Chemotherapy, radiotherapy, targeted therapy, and immunotherapy are established cancer
treatment modalities that are widely used due to their demonstrated efficacy against tumors …
treatment modalities that are widely used due to their demonstrated efficacy against tumors …
Hypoxia-mediated chemotaxis and residence of macrophage in decidua by secreting VEGFA and CCL2 during normal pregnancy
XY Qin, HH Shen, XY Zhang, X Zhang, F Xie… - …, 2023 - rep.bioscientifica.com
In brief Hypoxia is vital for the establishment of the maternal–fetal interface during early
pregnancy. This study shows that decidual macrophages (dMφ) could be recruited and …
pregnancy. This study shows that decidual macrophages (dMφ) could be recruited and …
Hypoxia and connectivity in the developing vertebrate nervous system
JL Bonkowsky, JH Son - Disease Models & Mechanisms, 2018 - journals.biologists.com
The developing nervous system depends upon precise regulation of oxygen levels.
Hypoxia, the condition of low oxygen concentration, can interrupt developmental sequences …
Hypoxia, the condition of low oxygen concentration, can interrupt developmental sequences …
[HTML][HTML] Salidroside protects hypoxia-induced injury by up-regulation of miR-210 in rat neural stem cells
R Yan, H Xu, X Fu - Biomedicine & Pharmacotherapy, 2018 - Elsevier
Neonatal brain hypoxia is a disease that affects the nervous system in children. Salidroside
is a compound that has an anti-hypoxic effect, but the mechanism of salidroside in neonatal …
is a compound that has an anti-hypoxic effect, but the mechanism of salidroside in neonatal …
[HTML][HTML] Hypoxia-induced MicroRNA-429 promotes differentiation of MC3T3-E1 osteoblastic cells by mediating ZFPM2 expression
J Huang, J Peng, G Cao, S Lu, L Liu, Z Li… - Cellular Physiology and …, 2016 - karger.com
Background/Aims: Hypoxia has been reported to regulate osteoblastic differentiation of bone
cells and cartilage development. However, information concerning the molecular …
cells and cartilage development. However, information concerning the molecular …
MicroRNA‑30a increases the chemosensitivity of U251 glioblastoma cells to temozolomide by directly targeting beclin 1 and inhibiting autophagy
J Xu, H Huang, R Peng, X Ding… - Experimental and …, 2018 - spandidos-publications.com
Temozolomide (TMZ) is one of the most commonly used drugs for the clinical treatment of
glioblastomas. However, it has been reported that treatment with TMZ can induce …
glioblastomas. However, it has been reported that treatment with TMZ can induce …
LncRNA MIAT facilitated BM-MSCs differentiation into endothelial cells and restored erectile dysfunction via targeting miR-200a in a rat model of erectile dysfunction
XG Ding, JJ Yang, S Li, H Zheng, CH Gu, ZK Jia… - European Journal of …, 2018 - Elsevier
Background Bone-marrow derived mesenchymal stem cells (BM-MSCs) implantation
effectively restored rats' erectile dysfunction (ED). Long noncoding RNA (LncRNA) …
effectively restored rats' erectile dysfunction (ED). Long noncoding RNA (LncRNA) …