Abstract MicroRNA-429 (miR-429) plays an important role in mesenchymal stem cells.
Hypoxia-inducible factor 1α (HIF-1α) is a nuclear transcription factor that regulates the …

Scope Iron overload contributes to the pathogenesis of atherosclerosis and iron chelators
are beneficial through their antioxidant properties. Hepatic iron loading increases …

Heparanase (HPSE) and vascular endothelial growth factor (VEGF) are believed to play a
vital role in hypoxia-induced retinal neovascularization (RNV). HPSE is a target gene of miR …

MicroRNAs are reported to have a crucial role in the regulation of self-renewal and
differentiation of stem cells. Hypoxia has been identified as a key biophysical element of the …

Cardiovascular diseases, such as ischemic heart disease, remain the most common cause
of death worldwide. Regenerative medicine with stem cell therapy is a promising tool for …

Retinal neovascularization (RNV) is a prominent pathological angiogenesis, which causes
detrimental outcomes in visual functions. Previous literature represents that miR-132 …

MicroRNAs (miRNAs) have been documented as critical regulators in ischemia/reperfusion-
induced neuronal death. A better understanding of miRNA-mediated molecular mechanisms …

Background: A major obstacle to the treatment of soft tissue injuries is the hypovascular
nature of the tissues. Deferoxamine (DFO) has been shown to stimulate angiogenesis by …

Introduction: Several signaling pathways are activated during hypoxia to promote
angiogenesis, leading to endothelial cell patterning, interaction, and downstream signaling …

Ischemic cardiomyopathy (ICM) is associated with abnormal microRNA expression levels
that involve an altered gene expression profile. However, little is known about the underlying …