The healthy heart does not control a specific cardiac output: a plea for a new interpretation of normal cardiac function

EJ Stöhr - American Journal of Physiology-Heart and …, 2022 - journals.physiology.org
The current evidence suggests that the healthy heart does not sense the optimal cardiac
output (Q̇) because the different organ systems that influence cardiac function do not …

Adrenergic control of skeletal muscle blood flow during chronic hypoxia in healthy males

LL Simpson, AB Hansen, G Moralez… - American Journal …, 2023 - journals.physiology.org
Sympathetic transduction is reduced following chronic high-altitude (HA) exposure;
however, vascular α-adrenergic signaling, the primary mechanism mediating sympathetic …

The 'normal'adjustment of oxygen delivery to small muscle mass exercise is not optimized for muscle contractile function

PJ Drouin, T Liu, LA Lew… - The Journal of …, 2023 - Wiley Online Library
Oxygen delivery is viewed as tightly coupled to demand in exercise below critical power
because increasing oxygen delivery does not increase VO 2 V_O_2. However, whether the …

Preserved exercising muscle oxygen delivery: demand matching after high altitude acclimatization: because of or in spite of elevated sympathetic activation?

ME Tschakovsky, PJ Drouin… - Journal of …, 2023 - search.ebscohost.com
Keywords: chronic hypoxia; exercise; oxygen delivery; sympathetic vasoconstriction EN
chronic hypoxia exercise oxygen delivery sympathetic vasoconstriction 381 383 3 01/17/23 …

Adrenergic restraint of blood flow and high‐altitude acclimatization.

OS Willoughby - Journal of Physiology, 2022 - search.ebscohost.com
Keywords: adrenergic; adrenergic blockade; exercise; high altitude; hypoxia;
vasoconstriction; vasodilation EN adrenergic adrenergic blockade exercise high altitude …

Vascular Reactivity to Rhythmic Handgrip at Altitude

L Maier - 2023 - era.library.ualberta.ca
Background: During exercise, there is an increase in sympathetic activity, causing
vasoconstriction and reduced blood flow. However, to maintain blood flow and oxygen …

[PDF][PDF] THE ROLE OF OXYGEN DELIVERY IN MEDIATING VOLUNTARY EXCITATION-CONTRACTION COUPLING: AN OXYGEN CONFORMING RESPONSE OF …

PJ Drouin - 2023 - qspace.library.queensu.ca
As we exercise long and/or hard enough, exercise related metabolites impair the ability of
muscle excitation to cause muscle contraction–reflecting an impairment of excitation …