Myocardial infarction and subsequent heart failure is a major health burden associated with
significant mortality and morbidity in western societies. The ability of cardiac tissue to …

Wnt signaling has diverse actions in cardiovascular development and disease processes.
Secreted frizzled-related protein 5 (Sfrp5) has been shown to function as an extracellular …

Atherosclerosis is the key pathogenesis of cardiovascular disease, which is a silent killer
and a leading cause of death in the United States. Atherosclerosis starts with the adhesion …

Coronary artery disease is an event of atherosclerosis characterized by a chronic vascular
inflammation. Risk factors like obesity, diabetes mellitus, hypertension, smoking …

Chronic inflammatory rheumatoid diseases (CIRD) such as rheumatoid arthritis, systemic
lupus erythematosus, and systemic sclerosis are an important risk factor for the development …

Abstract The coronavirus disease 2019 (COVID-19) remains a global public health
emergency. Despite being caused by severe acute respiratory syndrome coronavirus 2 …

Background Identifying the mechanistic pathways potentially associated with incident heart
failure (HF) may provide a basis for novel preventive strategies. Methods and Results To …

Chronic kidney disease (CKD) patients have an accelerated atherosclerosis, increased risk
of thrombotic-ischemic complications, and excessive mortality rates when compared with the …

Despite a technically perfect procedure, surgical stress can determine the success or failure
of an operation. Surgical trauma is often referred to as the “neglected step-child” of global …

Aims Proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitors are an emerging class
of low‐density lipoprotein cholesterol (LDL‐C)‐lowering agents. In spite of their known …