The role of damage-and pathogen-associated molecular patterns in inflammation-mediated vulnerability of atherosclerotic plaques

V Rai, DK Agrawal - Canadian journal of physiology and …, 2017 - cdnsciencepub.com
Atherosclerosis is a chronic inflammatory disease resulting in the formation of the
atherosclerotic plaque. Plaque formation starts with the inflammation in fatty streaks and …

Atherosclerosis is an inflammatory disease which lacks a common anti-inflammatory therapy: how human genetics can help to this issue. A narrative review

C Fava, M Montagnana - Frontiers in Pharmacology, 2018 - frontiersin.org
Atherosclerosis is a multifactorial disease triggered and sustained by different risk factors
such as dyslipidemia, arterial hypertension, diabetes mellitus, smoke, etc. Since a couple of …

Wound healing and cancer stem cells: inflammation as a driver of treatment resistance in breast cancer

KM Arnold, LM Opdenaker, D Flynn… - Cancer growth and …, 2015 - journals.sagepub.com
The relationship between wound healing and cancer has long been recognized. The
mechanisms that regulate wound healing have been shown to promote transformation and …

FABP4 activates the JAK2/STAT2 pathway via Rap1a in the homocysteine-induced macrophage inflammatory response in ApoE−/− mice atherosclerosis

L Xu, H Zhang, Y Wang, A Yang, X Dong, L Gu… - Laboratory …, 2022 - nature.com
Atherosclerosis is a chronic inflammatory vascular disease, and inflammation plays a critical
role in its formation and progression. Elevated serum homocysteine (Hcy) is an independent …

Randomization to plant-based dietary approaches leads to larger short-term improvements in Dietary Inflammatory Index scores and macronutrient intake compared …

GM Turner-McGrievy, MD Wirth, N Shivappa… - Nutrition research, 2015 - Elsevier
Studies have examined nutrient differences among people following different plant-based
diets. However, all of these studies have been observational. The aim of the present study …

Trajectories of function and biomarkers with age: the CHS All Stars Study

AB Newman, JL Sanders, JR Kizer… - International journal …, 2016 - academic.oup.com
Background: Multimorbidity is a major driver of physical and cognitive impairment, but rates
of decline are also related to ageing. We sought to determine trajectories of decline in a …

The GLP-1 analogue lixisenatide decreases atherosclerosis in insulin-resistant mice by modulating macrophage phenotype

Á Vinué, J Navarro, A Herrero-Cervera… - Diabetologia, 2017 - Springer
Aims/hypothesis Recent clinical studies indicate that glucagon-like peptide-1 (GLP-1)
analogues prevent acute cardiovascular events in type 2 diabetes mellitus but their …

An injectable thermosensitive hydrogel loaded with an ancient natural drug colchicine for myocardial repair after infarction

Y Chen, J Shi, Y Zhang, J Miao, Z Zhao, X Jin… - Journal of Materials …, 2020 - pubs.rsc.org
Localized administration of anti-inflammatory agents benefits patients after myocardial
infarction (MI) by repressing/modulating inflammatory response of the MI region and thus …

Early detection and treatment of the vulnerable coronary plaque: can we prevent acute coronary syndromes?

MJ Bom, DJ Van Der Heijden, E Kedhi… - Circulation …, 2017 - Am Heart Assoc
Early identification and treatment of the vulnerable plaque, that is, a coronary artery lesion
with a high likelihood of rupture leading to an acute coronary syndrome, have gained great …

Inflammation and atherosclerosis: cardiovascular evaluation in patients with autoimmune diseases

RO Escárcega, MJ Lipinski, M Garcia-Carrasco… - Autoimmunity …, 2018 - Elsevier
Evidence now indicates that inflammation contributes considerably to the initiation and
progression of atherosclerosis and active inflammatory processes may trigger plaque …