N6-methyladenosine and neurological diseases
N Zhang, C Ding, Y Zuo, Y Peng, L Zuo - Molecular Neurobiology, 2022 - Springer
Abstract N6-methyladenosine (m6A) is a dynamic reversible methylation modification of the
adenosine N6 position and is the most common chemical epigenetic modification among …
adenosine N6 position and is the most common chemical epigenetic modification among …
The m6A epitranscriptome on neural development and degeneration
YP Yen, JA Chen - Journal of biomedical science, 2021 - Springer
Abstract N 6-methyladenosine (m 6 A) is the most prevalent, conserved, and abundant RNA
modification of the mRNAs of most eukaryotes, including mammals. Similar to epigenetic …
modification of the mRNAs of most eukaryotes, including mammals. Similar to epigenetic …
Predicting RNA 5‐Methylcytosine Sites by Using Essential Sequence Features and Distributions
Methylation is one of the most common and considerable modifications in biological systems
mediated by multiple enzymes. Recent studies have shown that methylation has been …
mediated by multiple enzymes. Recent studies have shown that methylation has been …
Cerebroprotective Role of N6-Methyladenosine Demethylase FTO (Fat Mass and Obesity-Associated Protein) After Experimental Stroke
Background: FTO (fat mass and obesity-associated protein) demethylates N 6-
methyladenosine (m6A), which is a critical epitranscriptomic regulator of neuronal function …
methyladenosine (m6A), which is a critical epitranscriptomic regulator of neuronal function …
The potential roles of m6A modification in regulating the inflammatory response in microglia
Q Li, S Wen, W Ye, S Zhao, X Liu - Journal of neuroinflammation, 2021 - Springer
Background Microglia are key regulators of the inflammatory response in the brain.
Adenosine in RNAs can be converted to m 6 A (N 6-methyladenosine), which regulates RNA …
Adenosine in RNAs can be converted to m 6 A (N 6-methyladenosine), which regulates RNA …
Context-dependent roles of RNA modifications in stress responses and diseases
RNA modifications are diverse post-transcriptional modifications that regulate RNA
metabolism and gene expression. RNA modifications, and the writers, erasers, and readers …
metabolism and gene expression. RNA modifications, and the writers, erasers, and readers …
Mapping the m1A, m5C, m6A and m7G methylation atlas in zebrafish brain under hypoxic conditions by MeRIP-seq
W Li, X Li, X Ma, W Xiao, J Zhang - BMC genomics, 2022 - Springer
Background The epigenetic modifications play important regulatory roles in tissue
development, maintenance of physiological functions and pathological process. RNA …
development, maintenance of physiological functions and pathological process. RNA …
Noncoding RNA crosstalk in brain health and diseases
The mammalian brain expresses several classes of noncoding RNAs (ncRNAs), including
long ncRNAs (lncRNAs), circular RNAs (circRNAs), and microRNAs (miRNAs). These …
long ncRNAs (lncRNAs), circular RNAs (circRNAs), and microRNAs (miRNAs). These …
Post-stroke depression: epigenetic and epitranscriptomic modifications and their interplay with gut microbiota
Epigenetic and epitranscriptomic modifications that regulate physiological processes of an
organism at the DNA and RNA levels, respectively, are novel therapeutic candidates for …
organism at the DNA and RNA levels, respectively, are novel therapeutic candidates for …
Differential methylation of circRNA m6A in an APP/PS1 Alzheimer's disease mouse model
X Zhang, S Yang, S Han, Y Sun… - Molecular …, 2023 - spandidos-publications.com
Alzheimer's disease (AD) is a chronic neurological disease characterized by memory loss
and progressive cognitive impairment. The characteristic AD pathologies include …
and progressive cognitive impairment. The characteristic AD pathologies include …