Transient left ventricular (LV) dysfunction can occur after hypothermic hyperkalemic
cardioplegic arrest. This laboratory has developed an isolated LV myocyte system of …

Objective: Esmolol, an ultra-short-acting β-blocker, is known to attenuate myocardial
ischemia-reperfusion injury. The aim of this study was to compare the effects of esmolol and …

Administration of 3, 5, 3′-triiodo-L-thyronine (T3) has recently been suggested to acutely
improve left ventricular performance. However, the cellular and molecular mechanisms …

Background. Left ventricular dysfunction is frequently observed in patients after hypothermic
cardioplegic arrest, and often inotropic intervention is necessary for patients to be …

Background. Four experimental protocols were carried out to assess the ability of esmolol to
induce and maintain reversible cardiac arrest under continuous normothermic (37° C) …

Background Left ventricular (LV) dysfunction can occur after hyperkalemic cardioplegic
arrest and subsequent reperfusion and rewarming. Activation of adenosine triphosphate …

BACKGROUND: Hyperkalemic cardioplegia (Plegisol) has been shown to result in myocyte
swelling and reduced contractility. We have demonstrated the elimination of these …

Background Acute left ventricular dysfunction is commonly encountered after hypothermic,
hyperkalemic cardioplegic arrest (HHCA) and often requires inotropic intervention for …

The aims of this study were to assess (1) whether contractile dysfunction caused by
ischaemia under hyperkalaemic conditions (“cardioplegic ischaemia”) is associated with …

Transient left ventricular (LV) dysfunction can occur after cardioplegic arrest. The
contributory mechanisms for this phenomenon are not completely understood. We tested the …