[HTML][HTML] Overview of cisplatin-induced neurotoxicity and ototoxicity, and the protective agents

NAG Dos Santos, RS Ferreira… - Food and chemical …, 2020 - Elsevier
Cisplatin has dramatically improved the survival rate of cancer patients, but it has also
increased the prevalence of hearing and neurological deficits in this population. Cisplatin …

Juglans regia Linn.: A Natural Repository of Vital Phytochemical and Pharmacological Compounds

AA Bhat, A Shakeel, S Rafiq, I Farooq, AQ Malik… - Life, 2023 - mdpi.com
Juglans regia Linn. is a valuable medicinal plant that possesses the therapeutic potential to
treat a wide range of diseases in humans. It has been known to have significant nutritional …

A review on phytochemical composition and potential health-promoting properties of walnuts

THD Nguyen, DC Vu - Food Reviews International, 2023 - Taylor & Francis
Walnuts are among the commonly consumed oil nuts in the world. The nuts typically contain
40–70% oil, and are a rich source of fatty acids, phenolics, phytosterols, tocopherols and …

Role of inflammation and oxidative stress in chemotherapy-induced neurotoxicity

P Gupta, TK Makkar, L Goel, M Pahuja - Immunologic Research, 2022 - Springer
Chemotherapeutic agents may adversely affect the nervous system, including the neural
precursor cells as well as the white matter. Although the mechanisms are not completely …

[PDF][PDF] Chemical constituents, nutritional, pharmacological and therapeutic importance of Juglans regia-A review

AE Al-Snafi - IOSR Journal of Pharmacy, 2018 - med.utq.edu.iq
The phytochemical analysis of the bark of Juglans regia showed that it contained reducing
sugars, alkaloid, tannins, phenols and saponins. Preliminary phytochemical test of the …

Phytochemical profile and biological activity of Juglans regia

N Panth, KR Paudel, R Karki - Journal of Integrative Medicine, 2016 - Elsevier
Abstract Juglans regia Linn.(Juglandaceae), popularly known as English or Persian walnut,
is a valuable medicinal plant with a potency to cure various diseases in traditional medicine …

Protective role of epigallocatechin gallate in a rat model of cisplatin-induced cerebral inflammation and oxidative damage: impact of modulating NF-κB and Nrf2

MH Arafa, HH Atteia - Neurotoxicity research, 2020 - Springer
Cisplatin is a widely used chemotherapeutic agent in treating various types of cancers.
However, it can induce neurotoxicity and nephrotoxicity, limiting its dose and clinical use …

Walnut (Juglans regia L.) shell pyroligneous acid: chemical constituents and functional applications

A Jahanban-Esfahlan, R Amarowicz - RSC advances, 2018 - pubs.rsc.org
Upon the processing of different agricultural products, considerable amounts of by-products
and bio-wastes are produced and discarded or burnt as fuel, which are a potential source of …

Edaravone alleviates cisplatin-induced neurobehavioral deficits via modulation of oxidative stress and inflammatory mediators in the rat hippocampus

A Jangra, M Kwatra, T Singh, R Pant… - European Journal of …, 2016 - Elsevier
Cisplatin is a chemotherapeutic agent used in the treatment of malignant tumors. A major
clinical limitation of cisplatin is its potential toxic effects, including neurotoxicity. Edaravone …

Chemotherapy-induced cognitive impairments: A systematic review of the animal literature

A Matsos, IN Johnston - Neuroscience & Biobehavioral Reviews, 2019 - Elsevier
Whilst chemotherapy is a widely used anti-cancer treatment, a subset of patients experience
cognitive decline. However, cancer type, treatment regimen, fatigue and anxiety can …