The progress of fabrication designs of polymeric microneedles and related biomedical applications
X Jiang, W Zhang, R Terry, W Li - BMEMat, 2023 - Wiley Online Library
Microneedles (MNs) have been broadly used for transdermal delivery of a variety of drugs,
ranging from small chemicals to biological macromolecules, due to the properties of …
ranging from small chemicals to biological macromolecules, due to the properties of …
Biofilm microenvironment triggered self-enhancing photodynamic immunomodulatory microneedle for diabetic wound therapy
The treatment of diabetic wounds faces enormous challenges due to complex wound
environments, such as infected biofilms, excessive inflammation, and impaired …
environments, such as infected biofilms, excessive inflammation, and impaired …
Advances and Prospects for Hydrogel-Forming Microneedles in Transdermal Drug Delivery
X Hou, J Li, Y Hong, H Ruan, M Long, N Feng, Y Zhang - Biomedicines, 2023 - mdpi.com
Transdermal drug delivery (TDD) is one of the key approaches for treating diseases,
avoiding first-pass effects, reducing systemic adverse drug reactions and improving patient …
avoiding first-pass effects, reducing systemic adverse drug reactions and improving patient …
Multifunctional silk fibroin methacryloyl microneedle for diabetic wound healing
G Guan, Q Zhang, Z Jiang, J Liu, J Wan, P Jin, Q Lv - Small, 2022 - Wiley Online Library
Diabetic wound is one of the common complications in diabetic patients, which exhibits
chronic, hard‐to‐heal characteristics. The healing process of wounds is impaired by several …
chronic, hard‐to‐heal characteristics. The healing process of wounds is impaired by several …
Separable microneedles with photosynthesis-driven oxygen manufactory for diabetic wound healing
E Zhao, T Xiao, Y Tan, X Zhou, Y Li… - … Applied Materials & …, 2023 - ACS Publications
Oxygen plays an important role in diabetic chronic wound healing by regulating various life
activities such as cell proliferation, migration, and angiogenesis. Therefore, oxygen …
activities such as cell proliferation, migration, and angiogenesis. Therefore, oxygen …
Hyaluronic acid-based CuS nanoenzyme biodegradable microneedles for treating deep cutaneous fungal infection without drug resistance
B Wang, W Zhang, Q Pan, J Tao, S Li, T Jiang… - Nano …, 2023 - ACS Publications
Deep cutaneous fungal infection (DCFI) is difficult to be treated by the traditional topical
application due to low drug transdermal efficiency, poor fungicidal effect, and easy to …
application due to low drug transdermal efficiency, poor fungicidal effect, and easy to …
Rapid induction of long-lasting systemic and mucosal immunity via Thermostable Microneedle-Mediated Chitosan Oligosaccharide-Encapsulated DNA Nanoparticles
M Li, L Yang, C Wang, M Cui, Z Wen, Z Liao, Z Han… - Acs Nano, 2023 - ACS Publications
Most existing vaccines, delivered by intramuscular injection (IM), are typically associated
with stringent storage requirements under cold-chain distribution and professional …
with stringent storage requirements under cold-chain distribution and professional …
Investigation of the antibacterial properties of hyaluronic acid microneedles based on chitosan and MoS 2
W Du, X Li, M Zhang, G Ling, P Zhang - Journal of Materials Chemistry …, 2023 - pubs.rsc.org
Microneedle (MN) systems for painless transdermal drug delivery have been well developed
over the past few years to overcome the problems of subcutaneous injections. Hyaluronic …
over the past few years to overcome the problems of subcutaneous injections. Hyaluronic …
[HTML][HTML] pH-activatable oxidative stress amplifying dissolving microneedles for combined chemo-photodynamic therapy of melanoma
Y Huang, H Lai, J Jiang, X Xu, Z Zeng, L Ren… - Asian journal of …, 2022 - Elsevier
Photodynamic therapy (PDT)-mediated oxidation treatment is extremely attractive for skin
melanoma ablation, but the strong hydrophobicity and poor tumor selectivity of …
melanoma ablation, but the strong hydrophobicity and poor tumor selectivity of …
A microneedle-based delivery system for broad-protection seasonal influenza A DNA nanovaccines
L Wang, L Yang, F Zhang, X Liu, Q Xie, Q Liu… - Cell Reports Physical …, 2023 - cell.com
Seasonal influenza A viruses continue to pose a public health threat, and current vaccines
are not sufficiently effective because of virus mutation. There is an urgent need to develop a …
are not sufficiently effective because of virus mutation. There is an urgent need to develop a …