West syndrome: a comprehensive review

P Pavone, A Polizzi, SD Marino, G Corsello… - Neurological …, 2020 - Springer
Since its first clinical description (on his son) by William James West (1793–1848) in 1841,
and the definition of the classical triad of (1) infantile spasms;(2) hypsarrhythmia, and (3) …

Seizures in children

A Fine, EC Wirrell - Pediatrics in review, 2020 - publications.aap.org
Epilepsy is one of the most common neurologic disorders seen in children, with the highest
incidence in the first year of life. Diagnostic accuracy can be challenging because many …

Infantile spasms: a US consensus report

JM Pellock, R Hrachovy, S Shinnar, TZ Baram… - …, 2010 - Wiley Online Library
The diagnosis, evaluation, and management of infantile spasms (IS) continue to pose
significant challenges to the treating physician. Although an evidence‐based practice …

Cognitive and neurodevelopmental comorbidities in paediatric epilepsy

KC Nickels, MJ Zaccariello, LD Hamiwka… - Nature Reviews …, 2016 - nature.com
Cognitive and behavioural comorbidities are often seen in children with epilepsy, and are
more common and severe in refractory epilepsy. These comorbidities are associated with …

Epilepsy in children

R Guerrini - The Lancet, 2006 - thelancet.com
Summary 10· 5 million children worldwide are estimated to have active epilepsy. Over the
past 15 years, syndrome-oriented clinical and EEG diagnosis, and better aetiological …

Treatment of infantile spasms

EC Hancock, JP Osborne… - Cochrane Database of …, 2013 - cochranelibrary.com
Background Infantile spasms (West's Syndrome) is a syndrome that includes a peculiar type
of epileptic seizure—the spasms—and an electroencephalographic (EEG) abnormality often …

Infantile spasms: outcome in clinical studies

R Riikonen - Pediatric neurology, 2020 - Elsevier
Children with infantile spasms are likely to have a poor outcome. Outcome measures for
infantile spasms include primary response to treatment, relapse of spasms, neurological …

The United Kingdom Infantile Spasms Study (UKISS) comparing hormone treatment with vigabatrin on developmental and epilepsy outcomes to age 14 months: a …

AL Lux, SW Edwards, E Hancock, AL Johnson… - The Lancet …, 2005 - thelancet.com
Background Infantile spasms is a severe infantile seizure disorder that is difficult to treat and
has a high morbidity. Absence of spasms on days 13 and 14 after randomisation is more …

The descriptive epidemiology of infantile spasms among Atlanta children

E Trevathan, CC Murphy, M Yeargin‐Allsopp - Epilepsia, 1999 - Wiley Online Library
Purpose: To determine the population‐based epidemiology of infantile spasms (IS) among
Atlanta children. Methods: By using data from a cross‐sectional, population‐based …

Long-term outcome of patients with West syndrome

R Riikonen - Brain and Development, 2001 - Elsevier
The long-term outcome of Finnish children with West syndrome was evaluated. Two
hundred and fourteen patients were followed up for 20–35 years or until death. A third of the …