[HTML][HTML] The mechanism and therapy of aortic aneurysms

J Gao, H Cao, G Hu, Y Wu, Y Xu, H Cui, HS Lu… - Signal transduction and …, 2023 - nature.com
Aortic aneurysm is a chronic aortic disease affected by many factors. Although it is generally
asymptomatic, it poses a significant threat to human life due to a high risk of rupture …

[HTML][HTML] Immune and inflammatory mechanisms of abdominal aortic aneurysm

AC Marquez-Sanchez, EK Koltsova - Frontiers in immunology, 2022 - frontiersin.org
Abdominal aortic aneurysm (AAA) is a life-threatening cardiovascular disease. Immune-
mediated infiltration and a destruction of the aortic wall during AAA development plays …

Neutrophil extracellular traps induce abdominal aortic aneurysm formation by promoting the synthetic and proinflammatory smooth muscle cell phenotype via Hippo …

S Yang, L Chen, Z Wang, J Chen, Q Ni, X Guo… - Translational …, 2023 - Elsevier
The neutrophil plays an important role during abdominal aortic aneurysm (AAA) formation by
undergoing histone citrullination with peptidyl arginine deiminase 4 (encoded by Padi4) and …

[HTML][HTML] Building a better NET: Neutrophil extracellular trap targeted therapeutics in the treatment of infectious and inflammatory disorders

ATP Ngo, K Gollomp - Research and Practice in Thrombosis and …, 2022 - Elsevier
Infectious and inflammatory stimuli induce the release of neutrophil extracellular traps
(NETs), webs of cell‐free (cf) DNA complexed with histones and antimicrobial proteins, that …

[HTML][HTML] Blood immunological profile of abdominal aortic aneurysm based on autoimmune injury

H Huanggu, D Yang, Y Zheng - Autoimmunity Reviews, 2023 - Elsevier
Abdominal aortic aneurysm (AAA) occupies a large part of aorta aneurysm, and if there's no
timely intervention or treatment, the risks of rupture and death would rise sharply. With the …

[HTML][HTML] Neutrophil Extracellular Traps in Cardiovascular and Aortic Disease: A Narrative Review on Molecular Mechanisms and Therapeutic Targeting

N Ibrahim, W Eilenberg, C Neumayer… - International Journal of …, 2024 - mdpi.com
Neutrophil extracellular traps (NETs), composed of DNA, histones, and antimicrobial
proteins, are released by neutrophils in response to pathogens but are also recognized for …

Calprotectin as a new inflammatory marker of abdominal aortic aneurysm: A pilot study

E Plana, J Oto, R Herranz, P Medina… - Vascular …, 2024 - journals.sagepub.com
Introduction: Abdominal aortic aneurysm (AAA) is a relevant clinical problem due to the risk
of rupture of progressively dilated infrarenal aorta. It is characterized by degradation of …

ADAMTS-5 在加速形成中性粒细胞胞外陷阱恶化颅内动脉瘤疾病进展中的作用机制

张俊, 王巍, 王帮奎, 曾杰 - 实用医学杂志, 2023 - syyxzz.com
目的探讨ADAMTS-5 在加速形成中性粒细胞胞外陷阱恶化颅内动脉瘤疾病进展中的作用机制.
方法构建颅内动脉瘤小鼠模型. 采用腺病毒介导颅脑右侧脑池Willis 环动脉血管壁过表达或敲低 …

Neutrophils, Fast and Strong

GF Sud'ina - Biomedicines, 2022 - mdpi.com
The history of medicine is also the history of our understanding of the role of neutrophils in
protecting our bodies. Ilya I. Mechnikov discovered that phagocytes and phagocytosis are …

[PDF][PDF] Formation of neutrophil extracellular traps under hypoxia and in response to SARS-CoV-2

T Henneck - 2023 - elib.tiho-hannover.de
H2O Water H2O2 Hydrogen peroxide H3cit Citrullinated histone 3 HDL High density
lipoprotein HEK Human embryonic kidney HIF-1α Hypoxia inducible factor-1α HIV Human …