The blood–retina barrier in health and disease
F O'Leary, M Campbell - The FEBS journal, 2023 - Wiley Online Library
The blood–retina barrier (BRB) is the term used to define the properties of the retinal
capillaries and the retinal pigment epithelium (RPE), which separate the systemic circulation …
capillaries and the retinal pigment epithelium (RPE), which separate the systemic circulation …
Pericyte-endothelial interactions in the retinal microvasculature
H Huang - International journal of molecular sciences, 2020 - mdpi.com
Retinal microvasculature is crucial for the visual function of the neural retina. Pericytes and
endothelial cells (ECs) are the two main cellular constituents in the retinal microvessels …
endothelial cells (ECs) are the two main cellular constituents in the retinal microvessels …
Retinal findings in hospitalised patients with severe COVID-19
LA Pereira, LCM Soares, PA Nascimento… - British Journal of …, 2022 - bjo.bmj.com
Aim To identify retinal findings using dilated eye examination, which are possibly related to
SARS-CoV-2 infection in hospitalised patients with confirmed severe COVID-19. Methods In …
SARS-CoV-2 infection in hospitalised patients with confirmed severe COVID-19. Methods In …
Molecular mechanism of VEGF and its role in pathological angiogenesis
Over the last seven decades, a significant scientific contribution took place in the delineation
of the implications of vascular endothelial‐derived growth factor (VEGF) in the processes of …
of the implications of vascular endothelial‐derived growth factor (VEGF) in the processes of …
Paracentral acute middle maculopathy and the organization of the retinal capillary plexuses
The retinal capillary vasculature serves the formidable role of supplying the metabolically
active inner and middle retina. In the parafoveal region, the retinal capillary plexuses (RCP) …
active inner and middle retina. In the parafoveal region, the retinal capillary plexuses (RCP) …
Roles of HIFs and VEGF in angiogenesis in the retina and brain
Vascular development in the mammalian retina is a paradigm for CNS vascular
development in general, and its study is revealing fundamental mechanisms that explain the …
development in general, and its study is revealing fundamental mechanisms that explain the …
The impact of oxidative stress on blood-retinal barrier physiology in age-related macular degeneration
A Tisi, M Feligioni, M Passacantando, M Ciancaglini… - Cells, 2021 - mdpi.com
The blood retinal barrier (BRB) is a fundamental eye component, whose function is to select
the flow of molecules from the blood to the retina and vice-versa, and its integrity allows the …
the flow of molecules from the blood to the retina and vice-versa, and its integrity allows the …
Age-related macular degeneration: role of oxidative stress and blood vessels
Y Ruan, S Jiang, A Gericke - International journal of molecular sciences, 2021 - mdpi.com
Age-related macular degeneration (AMD) is a common irreversible ocular disease
characterized by vision impairment among older people. Many risk factors are related to …
characterized by vision impairment among older people. Many risk factors are related to …
Oxidative stress and vascular dysfunction in the retina: Therapeutic strategies
Y Ruan, S Jiang, A Musayeva, A Gericke - Antioxidants, 2020 - mdpi.com
Many retinal diseases, such as diabetic retinopathy, glaucoma, and age-related macular
(AMD) degeneration, are associated with elevated reactive oxygen species (ROS) levels …
(AMD) degeneration, are associated with elevated reactive oxygen species (ROS) levels …
Wnt Signaling in vascular eye diseases
The Wnt signaling pathway plays a pivotal role in vascular morphogenesis in various organs
including the eye. Wnt ligands and receptors are key regulators of ocular angiogenesis both …
including the eye. Wnt ligands and receptors are key regulators of ocular angiogenesis both …