Cannabis and cannabis edibles: a review

H Peng, F Shahidi - Journal of Agricultural and Food Chemistry, 2021 - ACS Publications
Cannabis is an excellent natural source of fiber and various bioactive cannabinoids. So far,
at least 120 cannabinoids have been identified, and more novel cannabinoids are gradually …

[HTML][HTML] Role of cannabidiol in the therapeutic intervention for substance use disorders

F Navarrete, MS García-Gutiérrez… - Frontiers in …, 2021 - frontiersin.org
Drug treatments available for the management of substance use disorders (SUD) present
multiple limitations in efficacy, lack of approved treatments or alarming relapse rates. These …

[HTML][HTML] Safety and toxicology of cannabinoids

J Sachs, E McGlade, D Yurgelun-Todd - Neurotherapeutics, 2015 - Elsevier
There is extensive research on the safety, toxicology, potency, and therapeutic potential of
cannabis. However, uncertainty remains facilitating continued debate on medical and …

[HTML][HTML] A reliable and validated LC-MS/MS method for the simultaneous quantification of 4 cannabinoids in 40 consumer products

Q Meng, B Buchanan, J Zuccolo, MM Poulin… - PLoS …, 2018 - journals.plos.org
In the past 50 years, Cannabis sativa (C. sativa) has gone from a substance essentially
prohibited worldwide to one that is gaining acceptance both culturally and legally in many …

[HTML][HTML] Cannabidiol enhances morphine antinociception, diminishes NMDA-mediated seizures and reduces stroke damage via the sigma 1 receptor

M Rodríguez-Muñoz, Y Onetti, E Cortés-Montero… - Molecular brain, 2018 - Springer
Cannabidiol (CBD), the major non-psychotomimetic compound present in the Cannabis
sativa plant, exhibits therapeutic potential for various human diseases, including chronic …

[HTML][HTML] Cannabidiol, a Cannabis sativa constituent, as an anxiolytic drug

ARM Schier, NPO Ribeiro, ACO Silva… - Brazilian Journal of …, 2012 - SciELO Brasil
OBJECTIVES: To review and describe studies of the non-psychotomimetic constituent of
Cannabis sativa, cannabidiol (CBD), as an anxiolytic drug and discuss its possible …

[HTML][HTML] Oral administration of cannabis with lipids leads to high levels of cannabinoids in the intestinal lymphatic system and prominent immunomodulation

A Zgair, JB Lee, JCM Wong, DA Taha, J Aram… - Scientific Reports, 2017 - nature.com
Abstract Cannabidiol (CBD) and∆ 9-tetrahydrocannabinol (THC) have well documented
immunomodulatory effects in vitro, but not following oral administration in humans. Here we …

[HTML][HTML] Tetrahydrocannabinol and cannabidiol medicines for chronic pain and mental health conditions

JD Henson, L Vitetta, S Hall - Inflammopharmacology, 2022 - Springer
Abstract Combination tetrahydrocannabinol (THC)/cannabidiol (CBD) medicines or CBD-
only medicines are prospective treatments for chronic pain, stress, anxiety, depression, and …

[HTML][HTML] Applications of Cannabis sativa L. in food and its therapeutic potential: From a prohibited drug to a nutritional supplement

A Iftikhar, U Zafar, W Ahmed, MA Shabbir, A Sameen… - Molecules, 2021 - mdpi.com
Hemp (Cannabis sativa L.) is a herbaceous anemophilous plant that belongs to the
Cannabinaceae family. The cannabis seed (hemp) has long been utilized as a food source …

[HTML][HTML] The heterogeneity and complexity of Cannabis extracts as antitumor agents

L Baram, E Peled, P Berman, B Yellin, E Besser… - Oncotarget, 2019 - ncbi.nlm.nih.gov
The Cannabis plant contains over 100 phytocannabinoids and hundreds of other
components. The biological effects and interplay of these Cannabis compounds are not fully …