For many years, the dogma has been that insulin resistance precedes the development of
hyperinsulinemia. However, recent data suggest a reverse order and place …

An emerging body of evidence suggests that an increased prevalence of insulin
abnormalities and insulin resistance in Alzheimer's disease may contribute to the disease …

OBJECTIVE To evaluate efficacy and safety of LixiLan (iGlarLixi), a novel titratable fixed-
ratio combination of insulin glargine (iGlar) and lixisenatide (Lixi), compared with both …

Although it is well established that type 2 diabetes (T2D) is generally due to the progressive
loss of β-cell insulin secretion against a background of insulin resistance, the actual …

Converging evidence has identified a potential association among Alzheimer's disease,
glucose metabolism, insulin activity, and memory. Notably, type 2 diabetes, which is …

La diabetes mellitus (DM) es una de las enfermedades con mayor impacto sociosanitario,
no sólo por su alta prevalencia, sino también por las complicaciones crónicas que produce …

Fasting in the Islamic month of Ramadan is obligatory for all sane, healthy adult Muslims.
The length of the day varies significantly in temperate regions—typically lasting≥ 18 h …

Chronic consumption of a high‐fat diet induces obesity and impairs the ultra‐structure of
organs and tissues. We examined the effect of sodium‐glucose cotransporter 2 (SGLT2) …

Impaired glucose tolerance and impaired fasting glucose form an intermediate stage in the
natural history of diabetes mellitus. From 10 to 15 percent of adults in the United States have …

Background Insulin therapy is often a delayed strategy in patients with type 2 diabetes
mellitus because it is associated with weight gain, hypoglycaemia, and the need for …