Late-onset Alzheimer's disease is a prevalent age-related polygenic disease that accounts
for 50-70% of dementia cases. Late-onset Alzheimer's disease is caused by a combination …

Introduction: Adaptogens are a group of plants that exhibit complex, nonspecific effects on
the human body, increasing its ability to adapt, develop resilience, and survive in stress …

There have been no new drugs for the treatment of schizophrenia in several decades and
treatment resistance represents a major unmet clinical need. The drugs that exist are based …

Noninvasive neuroimaging has revolutionized the study of the organization of the human
brain and how its structure and function are altered in psychiatric disorders. A critical …

A role for immune processes in the pathogenesis of schizophrenia has been suggested by
genetic and epidemiological studies, as well as cross-sectional studies on blood and brain …

Objective: The shared risk factors and clinical features in schizophrenia and bipolar disorder
may be linked via mitochondrial dysfunction. However, the severity of mitochondrial …

Genetic analyses for bipolar disorder (BD) have achieved prominent success in Europeans
in recent years, whereas its genetic basis in other populations remains relatively less …

Quantitative trait locus (QTL) analyses of multiomic molecular traits, such as gene
transcription (eQTL), DNA methylation (mQTL) and histone modification (haQTL), have been …

Despite strong evidence of heritability and growing discovery of genetic markers for major
mental illness, little is known about how gene expression in the brain differs across …

Genome-wide association studies (GWAS) for late stage age-related macular degeneration
(AMD) have identified 52 independent genetic variants with genome-wide significance at 34 …