Transforming growth factor-beta signaling in cancer-induced cachexia: from molecular pathways to the clinics
R Balsano, Z Kruize, M Lunardi, A Comandatore… - Cells, 2022 - mdpi.com
Cachexia is a metabolic syndrome consisting of massive loss of muscle mass and function
that has a severe impact on the quality of life and survival of cancer patients. Up to 20% of …
that has a severe impact on the quality of life and survival of cancer patients. Up to 20% of …
Natural products: Potential therapeutic agents to prevent skeletal muscle atrophy
The skeletal muscle (SkM) is the largest organ, which plays a vital role in controlling
musculature, locomotion, body heat regulation, physical strength, and metabolism of the …
musculature, locomotion, body heat regulation, physical strength, and metabolism of the …
Nutritional and exercise interventions in cancer-related cachexia: an extensive narrative review
VJ Clemente-Suárez, L Redondo-Flórez… - International Journal of …, 2022 - mdpi.com
One of the common traits found in cancer patients is malnutrition and cachexia, which affects
between 25% to 60% of the patients, depending on the type of cancer, diagnosis, and …
between 25% to 60% of the patients, depending on the type of cancer, diagnosis, and …
Chemotherapy-induced myopathy: the dark side of the cachexia sphere
Simple Summary In addition to cancer-related factors, anti-cancer chemotherapy treatment
can drive life-threatening body wasting in a syndrome known as cachexia. Emerging …
can drive life-threatening body wasting in a syndrome known as cachexia. Emerging …
Exercise medicine for cancer cachexia: Targeted exercise to counteract mechanisms and treatment side effects
Purpose Cancer-induced muscle wasting (ie, cancer cachexia, CC) is a common and
devastating syndrome that results in the death of more than 1 in 5 patients. Although …
devastating syndrome that results in the death of more than 1 in 5 patients. Although …
Recent advances in glycyrrhizin metabolism, health benefits, clinical effects and drug delivery systems for efficacy improvement; a comprehensive review
AF Bakr, P Shao, MA Farag - Phytomedicine, 2022 - Elsevier
Background Glycyrrhizin (GL) is a major active constituent of licorice root (Glycyrrhiza
glabra) that is considered one of the oldest and most frequently employed botanicals in …
glabra) that is considered one of the oldest and most frequently employed botanicals in …
Targeting mitochondria and oxidative stress in cancer-and chemotherapy-induced muscle wasting
Significance: Cancer is frequently associated with the early appearance of cachexia, a
multifactorial wasting syndrome. If not present at diagnosis, cachexia develops either as a …
multifactorial wasting syndrome. If not present at diagnosis, cachexia develops either as a …
Quercetin improved muscle mass and mitochondrial content in a murine model of cancer and chemotherapy-induced cachexia
BN VanderVeen, TD Cardaci, P Cunningham… - Nutrients, 2022 - mdpi.com
A cachexia diagnosis is associated with a doubling in hospital stay and increased
healthcare cost for cancer patients and most cachectic patients do not survive treatment …
healthcare cost for cancer patients and most cachectic patients do not survive treatment …
[HTML][HTML] Molecular mechanisms of cancer cachexia. Role of exercise training
E Tamayo-Torres, A Garrido, R de Cabo… - Molecular Aspects of …, 2024 - Elsevier
Cancer-associated cachexia represents a multifactorial syndrome mainly characterized by
muscle mass loss, which causes both a decrease in quality of life and anti-cancer therapy …
muscle mass loss, which causes both a decrease in quality of life and anti-cancer therapy …
Exercise counteracts the deleterious effects of cancer cachexia
Simple Summary This review provides an overview of the effects of exercise training on the
major mechanisms related to cancer cachexia (CC). The review also discusses how cancer …
major mechanisms related to cancer cachexia (CC). The review also discusses how cancer …