[HTML][HTML] PAMPs and DAMPs as the bridge between periodontitis and atherosclerosis: the potential therapeutic targets

X Zhu, H Huang, L Zhao - Frontiers in cell and developmental biology, 2022 - frontiersin.org
Atherosclerosis is a chronic artery disease characterized by plaque formation and vascular
inflammation, eventually leading to myocardial infarction and stroke. Innate immunity plays …

[HTML][HTML] Oral versus gastrointestinal mucosal immune niches in homeostasis and allostasis

LJ Suárez, S Arboleda, N Angelov… - Frontiers in Immunology, 2021 - frontiersin.org
Different body systems (epidermis, respiratory tract, cornea, oral cavity, and gastrointestinal
tract) are in continuous direct contact with innocuous and/or potentially harmful external …

[HTML][HTML] Nanoparticulate cell-free DNA scavenger for treating inflammatory bone loss in periodontitis

H Huang, W Pan, Y Wang, HS Kim, D Shao… - Nature …, 2022 - nature.com
Periodontitis is a common type of inflammatory bone loss and a risk factor for systemic
diseases. The pathogenesis of periodontitis involves inflammatory dysregulation, which …

[HTML][HTML] Quercetin preserves oral cavity health by mitigating inflammation and microbial dysbiosis

EC Mooney, SE Holden, XJ Xia, Y Li, M Jiang… - Frontiers in …, 2021 - frontiersin.org
Failure to attenuate inflammation coupled with consequent microbiota changes drives the
development of bone-destructive periodontitis. Quercetin, a plant-derived polyphenolic …

Salivary biomarkers in periodontitis patients: A pilot study

S Reddahi, A Bouziane, S Rida… - … Journal of Dentistry, 2022 - Wiley Online Library
Background and Objective. Periodontal disease is a chronic inflammatory condition,
involving the destruction of both soft and hard tissues in the periodontal region. Advances in …

Development of an immune‐related lncRNA–miRNA–mRNA network based on competing endogenous RNA in periodontitis

H Tang, S Yuan, T Chen, P Ji - Journal of Clinical …, 2021 - Wiley Online Library
Aim To explore the relationship between long non‐coding RNAs (lncRNAs) and immune
response and to construct an immune‐related competing endogenous RNA (ceRNA) …

Oral microbiome interactions with gingival gene expression patterns for apoptosis, autophagy and hypoxia pathways in progressing periodontitis

JL Ebersole, SS Kirakodu, OA Gonzalez - Immunology, 2021 - Wiley Online Library
Oral mucosal tissues must react with and respond to microbes comprising the oral
microbiome ecology. This study examined the interaction of the microbiome with …

[HTML][HTML] Genetically engineered cell membrane-coated nanoparticles for antibacterial and immunoregulatory dual-function treatment of ligature-induced periodontitis

Y Deng, M Ren, P He, F Liu, X Wang, C Zhou… - … in Bioengineering and …, 2023 - frontiersin.org
Periodontitis is an immune disease caused by bacterial infection and maintains a high
prevalence worldwide. However, conventional pharmacological treatments still present the …

[HTML][HTML] The Hippo pathway: a renewed insight in the craniofacial diseases and hard tissue remodeling

J Chen, J Cheng, C Zhao, B Zhao, J Mi… - International Journal of …, 2021 - ncbi.nlm.nih.gov
The Hippo pathway plays an important role in many pathophysiological processes, including
cell proliferation and differentiation, cell death, cell migration and invasion. Because of its …

[HTML][HTML] mTOR signaling in the regulation of CD4+ T cell subsets in periodontal diseases

Q Jiang, X Huang, W Yu, R Huang, X Zhao… - Frontiers in …, 2022 - frontiersin.org
Periodontal disease results from the inflammatory infiltration by the microbial community
which is marked through tooth mobility and alveolar bone resorption. The inflammation in …