Tissue transglutaminase (TG2) is a widely distributed multifunctional protein involved in a
broad range of cellular and metabolic functions carried out in a variety of cellular …

Carnitine is a medically needful nutrient that contributes in the production of energy and the
metabolism of fatty acids. Bioavailability is higher in vegetarians than in people who eat …

Multiple Sclerosis (MuS) is a disease caused due to an autoimmune attack against myelin
components in which non proteic mediators may play a role. Recent research in …

Peritoneal dialysis (PD) is a viable but under-prescribed treatment for uremic patients.
Concerns about its use include the bio-incompatibility of PD fluids, due to their potential for …

Due to lack of nuclei and de novo protein synthesis, post-translational modification (PTM) is
imperative for erythrocytes to regulate oxygen (O 2) delivery and combat tissue hypoxia …

Personalized medicine is the science of individualized prevention and therapy. In the last
decade, advances in high‐throughput approaches allowed the development of proteomic …

There is a growing interest on the role of autophagy in diabetes pathophysiology, where
development of neuropathy is one of the most frequent comorbidities. We have previously …

Ischemia–reperfusion injury contributes to the pathogenesis of many diseases, with acute
kidney injury included. Hibernating mammals survive prolonged bouts of deep torpor with a …

Oxidative stress is a well-described imbalance between the production of reactive oxygen
species (ROS) and the antioxidant defense system of cells and tissues. The overproduction …

Aims The tissue inhibitor of metalloproteinase TIMP3 is a stromal protein that restrains the
activity of both protease and receptor in the extracellular matrix and has been found to be …