The advantages of peritoneal dialysis (PD) over hemodialysis (HD) are well-documented.
Notwithstanding, only a small proportion of patients with end-stage renal disease (ESRD) …

Multiple sclerosis (MuS) is an autoimmune disease of the central nervous system
characterized by neuroinflammation, neurodegeneration, and degradation of the myelin …

Background: Carnitine deficiency is common in patients on dialysis. Serum free carnitine
concentration is significantly lower in patients on hemodialysis (HD) than in healthy …

Epidemiological data and research highlight increased neuropathy and chronic pain
prevalence among females, spanning metabolic and normometabolic contexts, including …

Prolonged exposure to palmitate impairs insulin secretion and leads to beta-cell death.
Some evidence suggests that palmitate could induce these effects through defects in …

Purpose The myocardium is largely dependent upon oxidation of fatty acids for the
production of ATP. Cardiac contractile abnormalities and failure have been reported after …

Carnitine deficiency contributes to developing various pathological conditions, such as
cardiac dysfunction, muscle weakness, and erythropoietin-resistant anemia in patients …

One of the significant organ systems which decline in aging is the kidney. While the causes
of age-associated decline in renal function are likely multifactorial, oxidative stress and …

Background: Carnitine supplementation improves various dialysis-related symptoms
including erythropoietin-resistant anemia in patients who are undergoing hemodialysis …

肉碱(carnitine, CN) 是一种非必需氨基酸, 参与长链脂肪酸向线粒体基质的转运, 经β-氧化,
产生能量. CN 的主要来源是饮食摄入, 肝脏和肾脏合成. 透析患者由于摄入减少 …