Colorectal cancer epidemiology: incidence, mortality, survival, and risk factors

FA Haggar, RP Boushey - Clinics in colon and rectal surgery, 2009 - thieme-connect.com
In this article, the incidence, mortality, and survival rates for colorectal cancer are reviewed,
with attention paid to regional variations and changes over time. A concise overview of …

Mitotic spindle misorientation in cancer–out of alignment and into the fire

JC Pease, JS Tirnauer - Journal of cell science, 2011 - journals.biologists.com
Mitotic spindle orientation can influence tissue organization and vice versa. Cells orient their
spindles by rotating them parallel or perpendicular to the cell–and hence the tissue–axis …

Prevalence of germline mutations in cancer predisposition genes in patients with pancreatic cancer

RC Grant, I Selander, AA Connor, S Selvarajah… - Gastroenterology, 2015 - Elsevier
Background & Aims We investigated the prevalence of germline mutations in APC, ATM,
BRCA1, BRCA2, CDKN2A, MLH1, MSH2, MSH6, PALB2, PMS2, PRSS1, STK11, and TP53 …

Colorectal cancer in the very young: a comparative study of tumor markers, pathology and survival in early onset and adult onset patients

SA Khan, M Morris, K Idrees, MI Gimbel… - Journal of pediatric …, 2016 - Elsevier
Introduction Colorectal cancer (CRC) diagnosed before age 30 years is a fatal disease
whose biology remains poorly understood. To understand its pathogenesis, we compared …

Colorectal cancer in the adolescent and young adult population

YN You, LD Lee, BW Deschner, D Shibata - JCO Oncology Practice, 2020 - ascopubs.org
Colorectal cancer in the young adult population is of increasing incidence and concern.
Genetic predisposition and heritable syndromes contribute to this trend, but perhaps more …

Genetic diversity, inbreeding and cancer

B Ujvari, M Klaassen, N Raven… - … of the Royal …, 2018 - royalsocietypublishing.org
Genetic diversity is essential for adaptive capacities, providing organisms with the potential
of successfully responding to intrinsic and extrinsic challenges. Although a clear reciprocal …

Colorectal cancer in adolescents and young adults: defining a growing threat

O Levine, K Zbuk - Pediatric blood & cancer, 2019 - Wiley Online Library
Colorectal cancer (CRC) incidence is rising among adolescents and young adults (AYAs),
with the greatest increase occurring in distal colon and rectal cancers. Reasons for this …

[HTML][HTML] Mutation spectrum of cancer-associated genes in patients with early onset of colorectal cancer

G Zhunussova, G Afonin, S Abdikerim… - Frontiers in …, 2019 - frontiersin.org
Background: Colorectal cancer (CRC) incidence is rising worldwide, as well as in the
Republic of Kazakhstan, while its occurrence is also increasing in the younger population …

Assessment of nutritional and inflammatory status to determine the prevalence of malnutrition in patients undergoing surgery for colorectal carcinoma

A Daniele, R Divella, I Abbate… - Anticancer …, 2017 - ar.iiarjournals.org
Background/Aim: Colorectal Cancer is the fourth most frequent cause of cancer death
worldwide and its incidence increases from 50 years of age. It is often associated with …

[HTML][HTML] Workplace exposure to diesel and gasoline engine exhausts and the risk of colorectal cancer in Canadian men

L Kachuri, PJ Villeneuve, MÉ Parent, KC Johnson… - Environmental …, 2016 - Springer
Abstract Background The International Agency for Research on Cancer (IARC) classified
diesel exhaust as carcinogenic to humans (Group 1) and gasoline exhaust as a possible …