Clinical pharmacology of non-steroidal anti-inflammatory drugs: a review
Non-steroidal anti-inflammatory drugs (NSAIDs) are a group of often chemically unrelated
compounds with some common therapeutic actions and side effects. They have potent anti …
compounds with some common therapeutic actions and side effects. They have potent anti …
Application of nanotechnology in the early diagnosis and comprehensive treatment of gastrointestinal cancer
S Deng, J Gu, Z Jiang, Y Cao, F Mao, Y Xue… - Journal of …, 2022 - Springer
Gastrointestinal cancer (GIC) is a common malignant tumour of the digestive system that
seriously threatens human health. Due to the unique organ structure of the gastrointestinal …
seriously threatens human health. Due to the unique organ structure of the gastrointestinal …
Effects of statins and farnesyltransferase inhibitors on the development and progression of cancer
MR Graaf, DJ Richel, CJF van Noorden… - Cancer treatment …, 2004 - Elsevier
Statins (3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors–HMG-CoA reductase
inhibitors) have been approved for the treatment of lipid disorders. Recently, in vivo studies …
inhibitors) have been approved for the treatment of lipid disorders. Recently, in vivo studies …
Non-steroidal anti-inflammatory drug use and the risk of gastric cancer: a systematic review and meta-analysis
WH Wang, JQ Huang, GF Zheng… - Journal of the …, 2003 - academic.oup.com
Background: The relationship between the use of non-steroidal anti-inflammatory drugs
(NSAIDs), including aspirin, and the risk of gastric cancer has not been well studied. We …
(NSAIDs), including aspirin, and the risk of gastric cancer has not been well studied. We …
Barrett's oesophagus: epidemiology, cancer risk and implications for management
PJF De Jonge, M van Blankenstein, WM Grady… - Gut, 2014 - gut.bmj.com
Although endoscopic surveillance of patients with Barrett's oesophagus has been widely
implemented, its effectiveness is debateable. The recently reported low annual oesophageal …
implemented, its effectiveness is debateable. The recently reported low annual oesophageal …
NSAIDs Modulate CDKN2A, TP53, and DNA Content Risk for Progression to Esophageal Adenocarcinoma
PC Galipeau, X Li, PL Blount, CC Maley… - PLoS …, 2007 - journals.plos.org
Background Somatic genetic CDKN2A, TP53, and DNA content abnormalities are common
in many human cancers and their precursors, including esophageal adenocarcinoma (EA) …
in many human cancers and their precursors, including esophageal adenocarcinoma (EA) …
Nonsteroidal anti-inflammatory drug use reduces risk of adenocarcinomas of the esophagus and esophagogastric junction in a pooled analysis
BACKGROUND & AIMS: Regular use of aspirin and other nonsteroidal anti-inflammatory
drugs (NSAIDs) has been reported to reduce risks of esophageal adenocarcinoma (EAC) …
drugs (NSAIDs) has been reported to reduce risks of esophageal adenocarcinoma (EAC) …
Wnt/β‐catenin‐pathway as a molecular target for future anti‐cancer therapeutics
S Dihlmann… - International journal of …, 2005 - Wiley Online Library
Conventional chemotherapeutic drugs used for the treatment of cancer patients in advanced
stages have yielded only limited benefit, regarding survival time not to mention cure of the …
stages have yielded only limited benefit, regarding survival time not to mention cure of the …
Acetylsalicylic acid-induced oxidative stress, cell cycle arrest, apoptosis and mitochondrial dysfunction in human hepatoma HepG2 cells
H Raza, A John, S Benedict - European journal of pharmacology, 2011 - Elsevier
It is widely accepted that non-steroidal anti-inflammatory drugs (NSAIDs), including aspirin,
reduce the risk of cancer. The anti-cancer and anti-inflammatory effects of NSAIDs are …
reduce the risk of cancer. The anti-cancer and anti-inflammatory effects of NSAIDs are …
Non-steroidal anti-inflammatory drugs and risk of neoplastic progression in Barrett's oesophagus: a prospective study
TL Vaughan, LM Dong, PL Blount, K Ayub… - The lancet …, 2005 - thelancet.com
Background Aspirin and other non-steroidal anti-inflammatory drugs (NSAID) probably
decrease the risk of colorectal neoplasia; however their effect on development of …
decrease the risk of colorectal neoplasia; however their effect on development of …