Secretory IgA has long been a divisive molecule. Some immunologists point to the mild
phenotype of IgA deficiency to justify ignoring it, while some consider its abundance and …

IgA mediates microbial homeostasis at the intestinal mucosa. Within the gut, IgA acts in a
context-dependent manner to both prevent and promote bacterial colonization and to …

As an emerging oxidant and disinfectant, peracetic acid (PAA) has increasingly been used
in wastewater treatment and the food and medical industries and has attracted greater …

Vaccine-induced high-avidity IgA can protect against bacterial enteropathogens by directly
neutralizing virulence factors or by poorly defined mechanisms that physically impede …

The emergence of antibiotic-resistant bacteria through mutations or the acquisition of
genetic material such as resistance plasmids represents a major public health issue …

Antibiotic treatment failure is of growing concern. Genetically encoded resistance is key in
driving this process. However, there is increasing evidence that bacterial antibiotic …

Increased levels of proteases, such as trypsin, in the distal intestine have been implicated in
intestinal pathological conditions,–. However, the players and mechanisms that underlie …

Bacterial virulence is highly dynamic and context-dependent. For this reason, it is
challenging to predict how molecular changes affect the growth of a pathogen in a host and …

Bacteriophage transfer (lysogenic conversion) promotes bacterial virulence evolution. There
is limited understanding of the factors that determine lysogenic conversion dynamics within …

Among antibodies, IgA is unique because it has evolved to be secreted onto mucosal
surfaces. The structure of IgA and the associated secretory component allow IgA to survive …