Promising derivatives of rutaecarpine with diverse pharmacological activities

D Li, Z Huang, X Xu, Y Li - Frontiers in Chemistry, 2023 - frontiersin.org
Rutaecarpine (RUT) is a natural pentacyclic indolopyridoquinazolinone alkaloid first isolated
from one of the most famous traditional Chinese herbs, Evodia rutaecarpa, which is used for …

Evodiamine: a privileged structure with broad-ranging biological activities

D Li, Y Li, X Jiang, W Liu, Q Zhao - Mini Reviews in Medicinal …, 2022 - ingentaconnect.com
Evodiamine (EVO) is a natural quinolone alkaloid firstly isolated from the fruit of Evodia
rutaecarpa, which is one of the most frequently used traditional Chinese herb for treating a …

Drug repurposing strategy II: from approved drugs to agri-fungicide leads

JX An, Y Ma, WB Zhao, YM Hu, YR Wang… - The Journal of …, 2023 - nature.com
Epidemic diseases of crops caused by fungi deeply affected the course of human history
and processed a major restriction on social and economic development. However, with the …

Discovery of novel salicylaldehyde derivatives incorporating an α‐methylene‐γ‐butyrolactone moiety as fungicidal agents

HW He, D Xu, KH Wu, ZY Lu, X Liu… - Pest Management …, 2023 - Wiley Online Library
BACKGROUND Plant diseases caused by phytopathogenic fungi and oomycetes pose a
serious threat to ensuring crop yield and quality. Finding novel fungicidal candidates based …

Design, synthesis, and biological evaluation of novel berberine derivatives against phytopathogenic fungi

Y Zhou, CJ Yang, XF Luo, AP Li… - Pest Management …, 2022 - Wiley Online Library
BACKGROUND The abuse of chemical fungicides not only leads to toxic residues and
resistance in plant pathogenic fungi, but also causes environmental pollution and side …

NADES blend for bioactive coating design as a sustainable strategy for postharvest control

J Boiteux, M Espino, S Azcarate, MF Silva, FJV Gomez… - Food Chemistry, 2023 - Elsevier
Bioactive functional coatings constitute a trendy topic due to they reduce postharvest fruit
losses worldwide. Also, they could be carriers of biocompounds providing health benefits to …

Discovery and Development of 4-Hydroxyphenylpyruvate Dioxygenase as a Novel Crop Fungicide Target

XH Yu, J Dong, CP Fan, MX Chen, M Li… - Journal of Agricultural …, 2023 - ACS Publications
Plant pathogenic fungi pose a significant threat to crop yields and quality, and the
emergence of fungicide resistance has further exacerbated the problem in agriculture …

Discovery of Novel Carboxamide Derivatives Containing Biphenyl Pharmacophore as Potential Fungicidal Agents Used for Resistance Management

S Ke, Z Gao, Z Zhang, F Liu, S Wen… - Journal of Agricultural …, 2023 - ACS Publications
Natural products are one of the main sources of drug and agrochemicals discovery.
Biphenyls skeleton are ubiquitous structures in many classes of natural products, which …

[HTML][HTML] Rutaecarpine analogues with potent anti-inflammation to alleviate acute ulcerative colitis via regulating TLR4/MAPK/NF-κB pathway

LQ Qin, ZY Gu, NY Chen, PD Liu, LS Lan, XW Li… - Results in …, 2024 - Elsevier
Natural products are a rich resource in drug discovery. In the report, series novel
rutaecarpine-derived compounds with potent anti-inflammatory activity and therapeutic …

Development of 1, 3, 4-oxadiazole derived antifungal agents and their application in maize diseases control

L Yao, G Zhang, L Yu, S Liu, X Wang, T Fan… - Frontiers in Plant …, 2022 - frontiersin.org
Maize is an important food crop and its fungal disease has become a limiting factor to
improve the yield and quality of maize. In the control of plant pathogens, commercial …