High-throughput sequencing, also known as next-generation sequencing (NGS), has
revolutionized genomic research. In recent years, NGS technology has steadily improved …

Gastric cancer is one of the most common malignancies and remains the second leading
cause of cancer-related death worldwide. Over 70% of new cases and deaths occur in …

DNA methylation patterns are altered in numerous diseases and often correlate with
clinically relevant information such as disease subtypes, prognosis and drug response. With …

Understanding how organisms cope with global change is a major scientific challenge. The
molecular pathways underlying rapid adaptive phenotypic responses to global change …

Purpose Social inequalities are widely accepted to have a deleterious effect on children's
mental health, and those with lower socioeconomic status generally experience more …

Interpreting the function and metabolism of enzymatic DNA modifications requires both
position-specific and global quantities. Sequencing-based techniques that deliver the former …

DNA methylation is one of the epigenetic changes, which plays a major role in regulating
gene expression and, thus, many biological processes and diseases. There are several …

Epigenetic mechanisms are an underappreciated and often ignored component of an
organism's response to environmental change and may underlie many types of phenotypic …

Insects are one of the most successful classes on Earth, reflected in an enormous species
richness and diversity. Arguably, this success is partly due to the high degree to which …

Remarkable progress in the field of epigenetics has turned academic, medical and public
attention to the potential applications of these new advances in medicine and various fields …