Proper growth and branching of dendrites are crucial for adequate central nervous system
(CNS) functioning. The neuronal dendritic geometry determines the mode and quality of …

Growth cones at the tips of extending axons navigate through developing organisms by
probing extracellular cues, which guide them through intermediate steps and onto final …

Neuregulins (NRGs) are EGF-like ligands associated with cognitive disorders. Unprocessed
proNRG3 is cleaved by BACE1 to generate the mature membrane-bound NRG3 ligand, but …

Introduction Neuregulin-1 (NRG-1) appears to play a role in the pathogenesis of several
neuropsychiatric disorders, including epilepsy. We conducted a study to investigate the …

Chronic pelvic pain (CPP) in women with no obvious pelvic pathology has few evidence-
based treatment options. Our recent multicenter randomized controlled trial (GaPP2) in …

Schizophrenia is associated with altered cortical circuitry. Although the schizophrenia risk
gene NRG1 is known to affect the wiring of inhibitory interneurons, its role in excitatory …

Neuregulins (NRGs) signal via ErbB receptors to regulate neural development, excitability,
synaptic and network activity, and behaviors relevant to psychiatric disorders. Bidirectional …

The unique qualities of the human brain are a product of a complex evolutionary process.
Evolution, famously described by François Jacob as a “tinkerer,” builds upon existing …

目的研究云南地区患有局灶性癫痫人群的神经调节因子1 (Neuregulin-1, NRG1)
及其受体ErbB4 基因的多态现象与局灶性癫痫易感性的关系. 方法采用癫痫病例组和健康对照组 …

Receptor protein tyrosine kinase (RTKs) play important roles in the peripheral as well as the
central nervous system. These receptors can alter large number of cellular functions by …