Management of asymptomatic sexually transmitted infections in Europe: towards a differentiated, evidence-based approach

C Kenyon, B Herrmann, G Hughes… - The Lancet Regional …, 2023 - thelancet.com
Most sexually transmitted infections (STIs) can be accurately diagnosed and treated during
asymptomatic carriage. Widespread screening for these STIs is therefore assumed to be an …

Neisseria gonorrhoeae vaccines: a contemporary overview

E Williams, KL Seib, CK Fairley… - Clinical Microbiology …, 2024 - Am Soc Microbiol
Neisseria gonorrhoeae infection is an important public health issue, with an annual global
incidence of 87 million. N. gonorrhoeae infection causes significant morbidity and can have …

Pelvic Inflammatory Disease Due to Neisseria gonorrhoeae and Chlamydia trachomatis: Immune Evasion Mechanisms and Pathogenic Disease Pathways

T Darville - The Journal of infectious diseases, 2021 - academic.oup.com
Pelvic inflammatory disease (PID) results from ascension of sexually transmitted pathogens
from the lower genital tract to the uterus and/or fallopian tubes in women, with potential …

4CMenB sustained vaccine effectiveness against invasive meningococcal B disease and gonorrhoea at three years post programme implementation

B Wang, L Giles, P Andraweera, M McMillan… - Journal of Infection, 2023 - Elsevier
Objectives To evaluate persistence of vaccine effectiveness (VE) and vaccine impact (VI) on
invasive meningococcal B (MenB) disease and gonorrhoea at three years after …

Mechanisms of host manipulation by Neisseria gonorrhoeae

E Walker, S van Niekerk, K Hanning, W Kelton… - Frontiers in …, 2023 - frontiersin.org
Neisseria gonorrhoeae (also known as gonococcus) has been causing gonorrhoea in
humans since ancient Egyptian times. Today, global gonorrhoea infections are rising at an …

The serogroup B meningococcal outer membrane vesicle-based vaccine 4CMenB induces cross-species protection against Neisseria gonorrhoeae

I Leduc, KL Connolly, A Begum, K Underwood… - PLoS …, 2020 - journals.plos.org
There is a pressing need for a gonorrhea vaccine due to the high disease burden
associated with gonococcal infections globally and the rapid evolution of antibiotic …

[HTML][HTML] Vaccine value profile for Neisseria gonorrhoeae

Y Lyu, A Choong, EPF Chow, KL Seib, HS Marshall… - Vaccine, 2024 - Elsevier
Neisseria gonorrhoeae infection (gonorrhoea) is a global public health challenge, causing
substantial sexual and reproductive health consequences, such as infertility, pregnancy …

Genomic and resistance epidemiology of Gram-negative bacteria in Africa: a systematic review and phylogenomic analyses from a one health perspective

J Osei Sekyere, MA Reta - Msystems, 2020 - Am Soc Microbiol
Antibiotic resistance (AR) remains a major threat to public and animal health globally.
However, AR ramifications in developing countries are worsened by limited molecular …

Vaccine candidates for the control and prevention of the sexually transmitted disease gonorrhea

EC Haese, VC Thai, CM Kahler - Vaccines, 2021 - mdpi.com
The World Health Organization (WHO) has placed N. gonorrhoeae on the global priority list
of antimicrobial resistant pathogens and is urgently seeking the development of new …

Galectins as potential therapeutic targets in STIs in the female genital tract

AL Lujan, DO Croci, GA Rabinovich… - Nature Reviews …, 2022 - nature.com
Every day, more than one million people worldwide acquire a sexually transmitted infection
(STI). This public health problem has a direct effect on women's reproductive and sexual …