The gut-brain axis in multiple sclerosis. Is its dysfunction a pathological trigger or a consequence of the disease?

B Parodi, N Kerlero de Rosbo - Frontiers in immunology, 2021 - frontiersin.org
A large and expending body of evidence indicates that the gut-brain axis likely plays a
crucial role in neurological diseases, including multiple sclerosis (MS). As a whole, the gut …

[HTML][HTML] Epilepsy and the gut: Perpetrator or victim?

M Al-Beltagi, NK Saeed - World Journal of Gastrointestinal …, 2022 - ncbi.nlm.nih.gov
The brain and the gut are linked together with a complex, bi-path link known as the gut-brain
axis through the central and enteric nervous systems. So, the brain directly affects and …

Causal atlas between inflammatory bowel disease and mental disorders: a bi-directional 2-sample Mendelian randomization study

X Yang, L Yang, T Zhang, H Zhang, H Chen… - Frontiers in …, 2023 - frontiersin.org
Background The brain-gut axis link has attracted increasing attention, with observational
studies suggesting that the relationship between common mental disorders and …

Mitochondrial DNA copy number is associated with Crohn's disease: a comprehensive Mendelian randomization analysis

X Cai, X Li, C Liang, M Zhang, Y Xu, Z Dong, Y Weng… - Scientific reports, 2023 - nature.com
Mitochondrial DNA plays a critical role in the pathophysiological process of inflammation.
However, the relationship between mitochondrial DNA copy number (mtDNA-CN) and …

Oat peptides alleviate dextran sulfate sodium salt-induced colitis by maintaining the intestinal barrier and modulating the Keap1-Nrf2 axis

ZH Ji, WY Xie, PS Zhao, HY Wu, WZ Ren, JP Hu… - Nutrients, 2023 - mdpi.com
The prevalence of inflammatory bowel disease (IBD) is progressively rising each year,
emphasizing the significance of implementing rational dietary interventions for disease …

Brain imaging derived phenotypes: a biomarker for the onset of inflammatory bowel disease and a potential mediator of mental complications

F Li, Q Zhao, T Tang, Y Liu, Z Wang, Z Wang… - Frontiers in …, 2024 - frontiersin.org
Background and aims Inflammatory bowel disease (IBD), mainly categorized into Crohn's
disease (CD) and ulcerative colitis (UC), is a chronic relapsing gastrointestinal disorder that …

[HTML][HTML] Peripheral diabetic neuropathy

MA Bodman, M Varacallo - StatPearls [Internet], 2023 - ncbi.nlm.nih.gov
Objectives: Review the pathophysiology of diabetic neuropathy. Summarize the treatment of
diabetic neuropathy. Describe the potential complications of diabetic neuropathy. Outline the …

The alleviative effect of C-phycocyanin peptides against TNBS-induced inflammatory bowel disease in zebrafish via the MAPK/Nrf2 signaling pathways

F Xu, F Yang, Y Qiu, C Wang, Q Zou, L Wang… - Fish & Shellfish …, 2024 - Elsevier
Introduction Ulcerative colitis (UC) is an incurable and highly complex chronic inflammatory
bowel disease (IBD) affecting millions of people worldwide. C-phycocyanin (C-PC) has been …

[HTML][HTML] Advancements in inflammatory bowel disease: A narrative review of diagnostics, management, epidemiology, prevalence, patient outcomes, quality of life …

MA Muzammil, FNU Fariha, T Patel, R Sohail, M Kumar… - Cureus, 2023 - ncbi.nlm.nih.gov
Inflammatory bowel disease (IBD), encompassing ulcerative colitis (UC) and Crohn's
disease (CD), is a chronic, immune-mediated disorder that impacts the gastrointestinal tract …

The interplay between microbiota and brain-gut axis in epilepsy treatment

H Zhu, W Wang, Y Li - Frontiers in Pharmacology, 2024 - frontiersin.org
The brain-gut axis plays a vital role in connecting the cognitive and emotional centers of the
brain with the intricate workings of the intestines. An imbalance in the microbiota-mediated …