Gastrointestinal satiety signals
OB Chaudhri, V Salem, KG Murphy… - Annu. Rev. Physiol …, 2008 - annualreviews.org
The increasing prevalence of obesity worldwide has imparted renewed impetus to the study
of the mechanisms of appetite regulation. Digestion and nutrient absorption take place in the …
of the mechanisms of appetite regulation. Digestion and nutrient absorption take place in the …
The gut–liver axis in the control of energy metabolism and food intake in animals
Recent research has convincingly demonstrated a bidirectional communication axis
between the gut and liver that enables the gut microbiota to strongly affect animals' feeding …
between the gut and liver that enables the gut microbiota to strongly affect animals' feeding …
The central role of hypothalamic inflammation in the acute illness response and cachexia
KG Burfeind, KA Michaelis, DL Marks - Seminars in cell & developmental …, 2016 - Elsevier
When challenged with a variety of inflammatory threats, multiple systems across the body
undergo physiological responses to promote defense and survival. The constellation of …
undergo physiological responses to promote defense and survival. The constellation of …
Developmental programming of hypothalamic feeding circuits
SG Bouret, RB Simerly - Clinical genetics, 2006 - Wiley Online Library
The hypothalamus plays a critical role in the regulation of food intake and body weight, and
recent work has defined a core circuitry in the hypothalamus that appears to mediate many …
recent work has defined a core circuitry in the hypothalamus that appears to mediate many …
Gastric bypass increases energy expenditure in rats
M Bueter, C Löwenstein, T Olbers, M Wang, NL Cluny… - Gastroenterology, 2010 - Elsevier
BACKGROUND & AIMS: Mechanisms underlying weight loss maintenance after gastric
bypass are poorly understood. Our aim was to examine the effects of gastric bypass on …
bypass are poorly understood. Our aim was to examine the effects of gastric bypass on …
Insulin and its evolving partnership with leptin in the hypothalamic control of energy homeostasis
KD Niswender, DG Baskin, MW Schwartz - Trends in Endocrinology & …, 2004 - cell.com
Despite an alarming increase in the burden of obesity worldwide, body adiposity seems to
be a regulated physiological variable. Regulation of adiposity occurs through a classical …
be a regulated physiological variable. Regulation of adiposity occurs through a classical …
The role of hypothalamic estrogen receptors in metabolic regulation
A Frank, LM Brown, DJ Clegg - Frontiers in neuroendocrinology, 2014 - Elsevier
Estrogens regulate key features of metabolism, including food intake, body weight, energy
expenditure, insulin sensitivity, leptin sensitivity, and body fat distribution. There are two …
expenditure, insulin sensitivity, leptin sensitivity, and body fat distribution. There are two …
Serotonin and the regulation of mammalian energy balance
MH Donovan, LH Tecott - Frontiers in neuroscience, 2013 - frontiersin.org
Maintenance of energy balance requires regulation of the amount and timing of food intake.
Decades of experiments utilizing pharmacological and later genetic manipulations have …
Decades of experiments utilizing pharmacological and later genetic manipulations have …
Current thoughts on maternal nutrition and fetal programming of the metabolic syndrome
B Brenseke, MR Prater, J Bahamonde… - Journal of …, 2013 - Wiley Online Library
Chronic diseases such as type 2 diabetes and cardiovascular disease are the leading cause
of death and disability worldwide. Although the metabolic syndrome has been defined in …
of death and disability worldwide. Although the metabolic syndrome has been defined in …
BDNF and the central control of feeding: accidental bystander or essential player?
M Rios - Trends in neurosciences, 2013 - cell.com
A considerable body of evidence links diminished brain-derived neurotrophic factor (BDNF)
signaling to energy balance dysregulation and severe obesity in humans and rodents …
signaling to energy balance dysregulation and severe obesity in humans and rodents …