BDNF and the central control of feeding: accidental bystander or essential player?
M Rios - Trends in neurosciences, 2013 - cell.com
A considerable body of evidence links diminished brain-derived neurotrophic factor (BDNF)
signaling to energy balance dysregulation and severe obesity in humans and rodents …
signaling to energy balance dysregulation and severe obesity in humans and rodents …
Metabolic programming of long‐term outcomes due to fatty acid nutrition in early life
SM Innis - Maternal & child nutrition, 2011 - Wiley Online Library
Understanding of the importance of dietary fatty acids has grown beyond a simple source of
energy to complex roles in regulating gene expression and cell and intracellular …
energy to complex roles in regulating gene expression and cell and intracellular …
Increased maternal nutrition alters development of the appetite‐regulating network in the brain
BS Muhlhausler, CL Adam, PA Findlay… - The FASEB …, 2006 - Wiley Online Library
Individuals exposed to an increased nutrient supply before birth have a high risk of
becoming obese children and adults. It has been proposed that exposure of the fetus to high …
becoming obese children and adults. It has been proposed that exposure of the fetus to high …
Minireview: leptin and development of hypothalamic feeding circuits
SG Bouret, RB Simerly - Endocrinology, 2004 - academic.oup.com
The arcuate nucleus of the hypothalamus (ARH) is a critical component of the forebrain
pathways that regulate energy homeostasis, and it plays a particularly important role in …
pathways that regulate energy homeostasis, and it plays a particularly important role in …
Lateral hypothalamic neuropeptides in reward and drug addiction
RJ DiLeone, D Georgescu, EJ Nestler - Life sciences, 2003 - Elsevier
The hypothalamus has been long considered important in feeding and other motivated
behaviors. The identification of neuropeptides expressed in the hypothalamus has initiated …
behaviors. The identification of neuropeptides expressed in the hypothalamus has initiated …
Differential accessibility of circulating leptin to individual hypothalamic sites
M Faouzi, R Leshan, M Björnholm… - …, 2007 - academic.oup.com
Hypothalamic neurons expressing the long form of the leptin receptor (LRb) mediate
important leptin actions. Although it has been suggested that leptin crosses the blood-brain …
important leptin actions. Although it has been suggested that leptin crosses the blood-brain …
Metabolic impact of sex hormones on obesity
Obesity and its associated health disorders and costs are increasing. Men and post-
menopausal women have greater risk of developing complications of obesity than younger …
menopausal women have greater risk of developing complications of obesity than younger …
Minireview: Gut peptides regulating satiety
The gastrointestinal tract and the pancreas release hormones regulating satiety and body
weight. Ghrelin stimulates appetite, and glucagon-like peptide-1, oxyntomodulin, peptide …
weight. Ghrelin stimulates appetite, and glucagon-like peptide-1, oxyntomodulin, peptide …
Proopiomelanocortin neurons in nucleus tractus solitarius are activated by visceral afferents: regulation by cholecystokinin and opioids
SM Appleyard, TW Bailey, MW Doyle… - Journal of …, 2005 - Soc Neuroscience
The nucleus tractus solitarius (NTS) receives dense terminations from cranial visceral
afferents, including those from the gastrointestinal (GI) system. Although the NTS integrates …
afferents, including those from the gastrointestinal (GI) system. Although the NTS integrates …
Ghrelin: more than a natural GH secretagogue and/or an orexigenic factor
E Ghigo, F Broglio, E Arvat, M Maccario… - Clinical …, 2005 - Wiley Online Library
Ghrelin, an acylated peptide produced predominantly by the stomach, has been discovered
to be a natural ligand of the growth hormone secretagogue receptor type 1a (GHS‐R1a) …
to be a natural ligand of the growth hormone secretagogue receptor type 1a (GHS‐R1a) …