New insights into the interplay between long non‐coding RNAs and RNA‐binding proteins in cancer
ZT Yao, YM Yang, MM Sun, Y He, L Liao… - Cancer …, 2022 - Wiley Online Library
With the development of proteomics and epigenetics, a large number of RNA‐binding
proteins (RBPs) have been discovered in recent years, and the interaction between long …
proteins (RBPs) have been discovered in recent years, and the interaction between long …
Cytoplasmic functions of long noncoding RNAs
Long noncoding RNAs (lncRNAs) are transcripts longer than 200 nucleotides found
throughout the cell that lack protein‐coding function. Their functions are closely linked to …
throughout the cell that lack protein‐coding function. Their functions are closely linked to …
Identification of HuR target circular RNAs uncovers suppression of PABPN1 translation by CircPABPN1
HuR influences gene expression programs and hence cellular phenotypes by binding to
hundreds of coding and noncoding linear RNAs. However, whether HuR binds to circular …
hundreds of coding and noncoding linear RNAs. However, whether HuR binds to circular …
[HTML][HTML] RNA-binding proteins in cancer: functional and therapeutic perspectives
D Kang, Y Lee, JS Lee - Cancers, 2020 - mdpi.com
Simple Summary RNA-binding proteins (RBPs) play central roles in regulating
posttranscriptional expression of genes. Many of them are known to be deregulated in a …
posttranscriptional expression of genes. Many of them are known to be deregulated in a …
[HTML][HTML] CircSMARCA5 regulates VEGFA mRNA splicing and angiogenesis in glioblastoma multiforme through the binding of SRSF1
D Barbagallo, A Caponnetto, D Brex, F Mirabella… - Cancers, 2019 - mdpi.com
Circular RNAs are a large group of RNAs whose cellular functions are still being
investigated. We recently proposed that circSMARCA5 acts as sponge for the splicing factor …
investigated. We recently proposed that circSMARCA5 acts as sponge for the splicing factor …
Long noncoding RNA OCC-1 suppresses cell growth through destabilizing HuR protein in colorectal cancer
Y Lan, X Xiao, Z He, Y Luo, C Wu, L Li… - Nucleic acids …, 2018 - academic.oup.com
Overexpressed in colon carcinoma-1 (OCC-1) is one of the earliest annotated long
noncoding RNAs (lncRNAs) in colorectal cancer (CRC); however, its function remains …
noncoding RNAs (lncRNAs) in colorectal cancer (CRC); however, its function remains …
[HTML][HTML] The regulation of protein translation and its implications for cancer
P Song, F Yang, H Jin, X Wang - Signal transduction and targeted …, 2021 - nature.com
In addition to the deregulation of gene transcriptions and post-translational protein
modifications, the aberrant translation from mRNAs to proteins plays an important role in the …
modifications, the aberrant translation from mRNAs to proteins plays an important role in the …
[HTML][HTML] LincRNA 1700020I14Rik alleviates cell proliferation and fibrosis in diabetic nephropathy via miR-34a-5p/Sirt1/HIF-1α signaling
A Li, R Peng, Y Sun, H Liu, H Peng, Z Zhang - Cell death & disease, 2018 - nature.com
Long intergenic noncoding RNAs (lincRNAs) have been gradually identified to be functional
in a variety of different mechanisms associating with development and epigenetic regulation …
in a variety of different mechanisms associating with development and epigenetic regulation …
[HTML][HTML] IGF2BP3 from physiology to cancer: novel discoveries, unsolved issues, and future perspectives
C Mancarella, K Scotlandi - Frontiers in cell and developmental …, 2020 - frontiersin.org
RNA network control is a key aspect of proper cellular homeostasis. In this context, RNA-
binding proteins (RBPs) play a major role as regulators of the RNA life cycle due to their …
binding proteins (RBPs) play a major role as regulators of the RNA life cycle due to their …
[HTML][HTML] The role of lncRNAs in gene expression regulation through mRNA stabilization
M Sebastian-delaCruz, I Gonzalez-Moro… - Non-coding RNA, 2021 - mdpi.com
mRNA stability influences gene expression and translation in almost all living organisms,
and the levels of mRNA molecules in the cell are determined by a balance between …
and the levels of mRNA molecules in the cell are determined by a balance between …