The mammalian target of rapamycin (mTOR) is a protein kinase that controls cellular
metabolism, catabolism, immune responses, autophagy, survival, proliferation, and …

The mechanistic target of rapamycin (mTOR) signaling pathway is a crucial cellular
signaling hub that, like the nervous system itself, integrates internal and external cues to …

Epilepsy is quite common in autism spectrum disorders, and it is increasingly recognized as
an additional clinical problem that must be dealt with. The rate of comorbidity varies …

Autism is a neurodevelopmental disorder characterized by social and communication
deficits, and repetitive behavior. Studies investigating the integrity of brain systems in autism …

Rett syndrome (RTT) is an autistic spectrum disorder with a known genetic basis. RTT is
caused by loss of function mutations in the X-linked gene MECP2 and is characterized by …

Tuberous sclerosis complex (TSC) is a congenital syndrome characterized by the
widespread development of benign tumors in multiple organs, caused by mutations in one of …

Objective To analyze the cumulative efficacy and safety of everolimus in treating
subependymal giant cell astrocytomas (SEGA) associated with tuberous sclerosis complex …

Tuberous sclerosis complex (TSC) involves abnormalities of the skin (hypomelanotic
macules, confetti skin lesions, facial angiofibromas, shagreen patches, fibrous cephalic …

Tuberous sclerosis complex (TSC) is associated with a wide range of behavioral,
psychiatric, intellectual, academic, neuropsychological, and psychosocial difficulties, which …

An elevated prevalence of atypical handedness (left-, mixed-, or non-right-handedness) has
been repeatedly reported in individuals with Autism Spectrum Disorder (ASD) compared to …