Tubulin inhibitors can interfere with normal cell mitosis and inhibit cell proliferation through
interfering with the normal structure and function of microtubules, forming spindle filaments …

The discovery of antifungal agents with novel structure, broad-spectrum, low toxicity, and
high efficiency has been the focus of medicinal chemists. Over the past decades, β-carboline …

Abstract α-Glucosidase is an important therapeutic target of diabetes mellitus. To find potent
α-glucosidase inhibitors, thirty-one β-carboline derivatives containing piperazine moieties …

This review is an informative and constructive resource for researchers interested in the
synthesis of β-carbolines. It provides a comprehensive overview of the various synthetic …

Abstract Cyclocarya paliurus (Batal.) leaves, which contain a range of bioactive compounds,
have been used as a traditional Chinese medicine homologous food since ancient times …

Leishmaniasis is one of today's most neglected diseases. The emergence of new anti-
leishmanial therapies emphasizes several study groups funded by the World Health …

The quest for novel antibacterial agents is imperative in the face of escalating antibiotic
resistance. Naturally occurring tetrahydro-β-carboline (THβC) alkaloids have been …

Herein, the synthesis and anticancer activity evaluation of a series of novel β-carbolines is
reported. The reactivity of nitrosoalkenes towards indole was explored for the synthesis of …

A serendipitous and highly efficient approach for the construction of a variety of δ-carboline
derivatives was developed through base-promoted cascade β-F-elimination …

Objectives The spread of antibiotic resistant bacteria is an important threat for human health.
Acinetobacter baumannii bacteria impose such a major issue, as multidrug-to pandrug …