[HTML][HTML] Browning of the white adipose tissue regulation: New insights into nutritional and metabolic relevance in health and diseases

SA Machado, G Pasquarelli-do-Nascimento… - Nutrition & …, 2022 - Springer
Adipose tissues are dynamic tissues that play crucial physiological roles in maintaining
health and homeostasis. Although white adipose tissue and brown adipose tissue are …

[HTML][HTML] Efficacy of popular diets applied by endurance athletes on sports performance: Beneficial or detrimental? A narrative review

A Devrim-Lanpir, L Hill, B Knechtle - Nutrients, 2021 - mdpi.com
Endurance athletes need a regular and well-detailed nutrition program in order to fill their
energy stores before training/racing, to provide nutritional support that will allow them to …

[HTML][HTML] Higd1a facilitates exercise-mediated alleviation of fatty liver in diet-induced obese mice

JY Zhu, M Chen, WJ Mu, HY Luo, L Guo - Metabolism, 2022 - Elsevier
Background Nonalcoholic fatty liver disease (NAFLD) has emerged as the most common
liver disease. Exercise is an effective strategy against NAFLD, but its underlying molecular …

[HTML][HTML] Adipokines as clinically relevant therapeutic targets in obesity

M Würfel, M Blüher, M Stumvoll, T Ebert, P Kovacs… - Biomedicines, 2023 - mdpi.com
Adipokines provide an outstanding role in the comprehensive etiology of obesity and may
link adipose tissue dysfunction to further metabolic and cardiovascular complications …

[HTML][HTML] Hepatic levels of S-adenosylmethionine regulate the adaptive response to fasting

A Capelo-Diz, S Lachiondo-Ortega… - Cell Metabolism, 2023 - cell.com
There has been an intense focus to uncover the molecular mechanisms by which fasting
triggers the adaptive cellular responses in the major organs of the body. Here, we show that …

[HTML][HTML] Newly discovered endocrine functions of the liver

J Rhyu, R Yu - World journal of hepatology, 2021 - ncbi.nlm.nih.gov
The liver, the largest solid visceral organ of the body, has numerous endocrine functions,
such as direct hormone and hepatokine production, hormone metabolism, synthesis of …

[HTML][HTML] Skeletal muscle and bone–emerging targets of fibroblast growth factor-21

H Sun, M Sherrier, H Li - Frontiers in physiology, 2021 - frontiersin.org
Fibroblast growth factor 21 (FGF21) is an atypical member of the FGF family, which functions
as a powerful endocrine and paracrine regulator of glucose and lipid metabolism. In addition …

[HTML][HTML] Pathogenic mitochondrial dysfunction and metabolic abnormalities

WH Moos, DV Faller, IP Glavas, DN Harpp… - Biochemical …, 2021 - Elsevier
Herein we trace links between biochemical pathways, pathogenesis, and metabolic
diseases to set the stage for new therapeutic advances. Cellular and acellular …

[HTML][HTML] Bupleuri radix extract ameliorates impaired lipid metabolism in high-fat diet-induced obese mice via gut microbia-mediated regulation of FGF21 signaling …

L Wu, Q Yan, F Chen, C Cao, S Wang - Biomedicine & Pharmacotherapy, 2021 - Elsevier
Background Obesity and its comorbidities are associated with abnormal lipid metabolism
and gut microbiota dysbiosis. Bupleuri Radix is a medicinal plant used in traditional Chinese …

[HTML][HTML] Phytochemicals from the cocoa shell modulate mitochondrial function, lipid and glucose metabolism in hepatocytes via activation of FGF21/ERK, AKT, and …

M Rebollo-Hernanz, Y Aguilera, MA Martin-Cabrejas… - Antioxidants, 2022 - mdpi.com
The cocoa shell is a by-product that may be revalorized as a source of bioactive compounds
to prevent chronic cardiometabolic diseases. This study aimed to investigate the …