Amyotrophic lateral sclerosis is a fatal CNS neurodegenerative disease. Despite intensive
research, current management of amyotrophic lateral sclerosis remains suboptimal from …

The diagnosis of amyotrophic lateral sclerosis can be challenging due to its heterogeneity in
clinical presentation and overlap with other neurological disorders. Diagnosis early in the …

Introduction Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder associated
with cognitive and behavioral impairments and motor symptoms. Magnetic resonance …

Background and Objectives A significant overlap between amyotrophic lateral sclerosis
(ALS) and behavioral variant of frontotemporal dementia (bvFTD) has been observed at …

Frontotemporal involvement has been extensively investigated in amyotrophic lateral
sclerosis (ALS) but remains relatively poorly characterized in other motor neuron disease …

Background Bulbar dysfunction is a cardinal feature of ALS with important quality of life and
management implications. The objective of this study is the longitudinal evaluation of a large …

Motor neuron diseases encompass a divergent group of conditions with considerable
differences in clinical manifestations, survival, and genetic vulnerability. One of the key …

Amyotrophic lateral sclerosis (ALS) has traditionally been associated with brain damage
involving the primary motor cortices and corticospinal tracts. In the recent decades, most of …

Conclusions To date, the research on humoral, radiological, neurophysiological, and
genetic correlates of neuropsychological alterations is at the early stage, and no conclusive …

Amyotrophic lateral sclerosis (ALS) is a multisystem neurodegenerative disorder
characterized by progressive degeneration of upper motor neurons and lower motor …