[HTML][HTML] Ethanol-mediated stress promotes autophagic survival and aggressiveness of colon cancer cells via activation of Nrf2/HO-1 pathway

C Cernigliaro, A D'Anneo, D Carlisi, M Giuliano… - Cancers, 2019 - mdpi.com
Epidemiological studies suggest that chronic alcohol consumption is a lifestyle risk factor
strongly associated with colorectal cancer development and progression. The aim of the …

Other plant metabolites

D Jean-Louis, S Amos - Pharmacognosy, 2024 - Elsevier
Nature has provided a diverse array of secondary metabolites with intricate molecular
scaffolding and significant pharmacological properties. Lignins, lignans, polyketide, and …

[HTML][HTML] Reduction of oxidative stress through activating the Nrf2 mediated HO-1 antioxidant efficacy signaling pathway by MS15, an antimicrobial peptide from …

MM Khan, YK Kim, T Bilkis, JW Suh, DY Lee, JC Yoo - Antioxidants, 2020 - mdpi.com
The efficient culture and purification of antimicrobial peptides (AMPs), along with intense
antioxidant activity, have drawn the interest to study antioxidant activity mechanism. We …

[HTML][HTML] Understanding the role of p38 and JNK mediated MAPK pathway in response to UV-A induced photoaging in Caenorhabditis elegans

MI Prasanth, S Gayathri, JP Bhaskar, V Krishnan… - … of Photochemistry and …, 2020 - Elsevier
Premature aging of the skin, principally induced by the UV radiations is called as
photoaging, characterized by an increase in the level of ROS and the damage of the …

[HTML][HTML] A Preliminary Assessment of the Nutraceutical Potential of Acai Berry (Euterpe sp.) as a Potential Natural Treatment for Alzheimer's Disease

MN ALNasser, IR Mellor, WG Carter - Molecules, 2022 - mdpi.com
Alzheimer's disease (AD) is characterised by progressive neuronal atrophy and the loss of
neuronal function as a consequence of multiple pathomechanisms. Current AD treatments …

[HTML][HTML] Pentagalloylglucose reduces AGE-induced inflammation by activating Nrf2/HO-1 and inhibiting the JAK2/STAT3 pathway in mesangial cells

J Tong, J Fang, T Zhu, P Xiang, J Shang, L Chen… - Journal of …, 2021 - Elsevier
Pentagalloylglucose (PGG), a gallotannin polyphenolic compound, has been found to
possess a host of beneficial pharmacologic activities, such as anti-inflammatory and …

Pharmacological, biochemical and immunological studies on protective effect of mangiferin in 6-hydroxydopamine (6-OHDA)-induced Parkinson's disease in rats

PC Tiwari, MJ Chaudhary, R Pal… - Annals of …, 2021 - journals.sagepub.com
Background: Parkinson's disease is a neurodegenerative disorder and is marked by
inflammation and death of neurons in the striatum region of the midbrain. It has been …

Lariciresinol Displays Anti‐Diabetic Activity through Inhibition of α‐Glucosidase and Activation and Enhancement of Insulin Signaling

MB Alam, JS Ra, JY Lim, BR Song… - Molecular Nutrition & …, 2022 - Wiley Online Library
Scope The aim of this study is to investigate the antidiabetic effect of lariciresinol (LSR) in
C2C12 myotubes and streptozotocin (STZ)‐induced diabetic mice. Methods and results To …

[HTML][HTML] Lutein exerts antioxidant and anti-inflammatory effects and influences iron utilization of BV-2 microglia

R Pap, E Pandur, G Jánosa, K Sipos, A Agócs, J Deli - Antioxidants, 2021 - mdpi.com
Lutein is a tetraterpene carotenoid, which has been reported as an important antioxidant
and it is widely used as a supplement. Oxidative stress participates in many human …

Mactanamide and lariciresinol as radical scavengers and Fe2+ ion chelators–A DFT study

A Amić, DM Cagardová - Phytochemistry, 2022 - Elsevier
A DFT based kinetic study of radical dotOOH radical scavenging potency of mactanamide
(MA) and lariciresinol (LA), two natural polyphenols, indicates their nearly equal potential via …