Potential therapeutic effect of thymoquinone and/or bee pollen on fluvastatin-induced hepatitis in rats

AE Mohamed, MA El-Magd, KS El-Said… - Scientific reports, 2021 - nature.com
Hepatitis is one of earlier, but serious, signs of liver damage. High doses of statins for a long
time can induce hepatitis. This study aimed to evaluate and compare the therapeutic …

Hepatic histopathological and morphometric changes in male mice exposed to rosuvastatin from pre-puberty to adulthood: a possible adaptive hepatic response

JK Knorst, TF de Mello, AR Oltramari… - Drug and Chemical …, 2024 - Taylor & Francis
Lifestyle changes, such as poor eating habits and a reduction in physical exercise, have
impaired human lipid profiles. Statins are widely used to treat dyslipidemias, of which …

[PDF][PDF] Curcumin Attenuated Oxidative Stress and Inflammation on Hepatitis Induced of by Fluvastatin in Female Albino Rats.

RH Abu Khudir, MA El-Ghannam, AF Salama… - Alexandria Journal of …, 2019 - alexjvs.com
The liver is a multifunctional vital organ with the primary role in maintenance of body
homeostasis (Liu etal., 2012). The crucial role of liver in maintaining human health status …

Effect of simvastatin on the skeletal muscles of senile male albino rats and possible protective role of L-carnitine. A histological study

M Mehanna, EEDES Abd Allah… - Egyptian Journal of …, 2020 - journals.ekb.eg
Background: Hyperlipidemia is a disorder in metabolism which means an abnormal
increase in levels of lipids (as cholesterol) and lipid-protein in the blood. It is one of the risk …

Investigations of the histopathological changes of ibuprofen over dose intake on the albino mice liver tissues

AG Alzwawy - AIP Conference Proceedings, 2024 - pubs.aip.org
Our study aim is to investigate the histopathological changes associated with prolonged
administration of ibuprofen overdose orally intake on the albino mice liver tissues. Fifteen …

[PDF][PDF] Human glial fibrillary acidic protein gene promoter targets hepatic and pancreatic stellate cells in transgenic Bama mini-pigs

X Zhu, S Quan, J Nie, K Lu, S Lu - Pakistan Journal of Zoology, 2016 - zsp.com.pk
Hepatic and pancreatic stellate cells (HSCs and PSCs) have been considered to be closely
associated with the pathogenesis of fibrosis, offering a hopeful therapeutic target for treating …

Drug interactions between phenytoin and rosuvastatin on lipid profile, liver functions and oxidative stress biomarkers in irradiated rats

DM Lotfy, SHM Hassan, ME El Sayed… - The Egyptian Journal of …, 2015 - journals.ekb.eg
Background: phenytoin is one of the most commonly used anticonvulsants for treating
generalized tonic-clonic seizures and status epileptics. Rosuvastatin is a new generation …

Human glial fibrillary acidic protein gene promoter targets hepatic and pancreatic stellate cells in transgenic Bama mini-pigs.

ZXX Zhu XiangXing, QSN Quan ShouNeng… - 2016 - cabidigitallibrary.org
Hepatic and pancreatic stellate cells (HSCs and PSCs) have been considered to be closely
associated with the pathogenesis of fibrosis, offering a hopeful therapeutic target for treating …