Physiology, signaling, and pharmacology of galanin peptides and receptors: three decades of emerging diversity

R Lang, AL Gundlach, FE Holmes, SA Hobson… - Pharmacological …, 2015 - ASPET
Galanin was first identified 30 years ago as a" classic neuropeptide," with actions primarily
as a modulator of neurotransmission in the brain and peripheral nervous system. Other …

Cholinergic system during the progression of Alzheimer's disease: therapeutic implications

EJ Mufson, SE Counts, SE Perez… - Expert review of …, 2008 - Taylor & Francis
Alzheimer's disease (AD) is characterized by a progressive phenotypic downregulation of
markers within cholinergic basal forebrain (CBF) neurons, frank CBF cell loss and reduced …

The galanin peptide family: receptor pharmacology, pleiotropic biological actions, and implications in health and disease

R Lang, AL Gundlach, B Kofler - Pharmacology & therapeutics, 2007 - Elsevier
The galanin peptide family consists of the “parental” galanin, galanin-message-associated
peptide (GMAP) which derives from the same peptide precursor gene product as galanin …

Galanin receptors and ligands

KEB Webling, J Runesson, T Bartfai… - Frontiers in …, 2012 - frontiersin.org
The neuropeptide galanin was first discovered 30 years ago. Today, the galanin family
consists of galanin, galanin-like peptide (GALP), galanin-message associated peptide …

Immunomodulatory role of neuropeptides in the cornea

S Puri, BM Kenyon, P Hamrah - Biomedicines, 2022 - mdpi.com
The transparency of the cornea along with its dense sensory innervation and resident
leukocyte populations make it an ideal tissue to study interactions between the nervous and …

Noradrenaline activation of neurotrophic pathways protects against neuronal amyloid toxicity

SE Counts, EJ Mufson - Journal of neurochemistry, 2010 - Wiley Online Library
J. Neurochem.(2010) 113, 649–660. Abstract Degeneration of locus coeruleus (LC)
noradrenergic forebrain projection neurons is an early feature of Alzheimer's disease. The …

Characterizing the neuroprotective effects of alkaline extract of Lycium barbarum on β-amyloid peptide neurotoxicity

YS Ho, MS Yu, CSW Lai, KF So, WH Yuen… - Brain research, 2007 - Elsevier
Lycium barbarum is an oriental medicinal herb that has long been used for its anti-aging and
cell-protective properties. Previous studies have shown that aqueous extracts from L …

[PDF][PDF] The galanin and galanin receptor subtypes, its regulatory role in the biological and pathological functions.

J ŠÍPKOVÁ, I KRAMÁRIKOVÁ… - Physiological …, 2017 - pdfs.semanticscholar.org
The multitalented neuropeptide galanin was first discovered 30 years ago but initially no
biologic activity was found. Further research studies discovered the presence of galanin in …

Circulating spexin levels negatively correlate with age, BMI, fasting glucose, and triglycerides in healthy adult women

C Lin, T Huang, L Zhao, LLD Zhong… - Journal of the …, 2018 - academic.oup.com
Context Spexin is a newly identified neuropeptide that is involved in satiety control, glucose,
and lipids metabolism. It has also been related to human diseases, such as obesity and type …

[HTML][HTML] Actions of β-amyloid protein on human neurons are expressed through the amylin receptor

JH Jhamandas, Z Li, D Westaway, J Yang… - The American journal of …, 2011 - Elsevier
Disruption of neurotoxic effects of amyloid β protein (Aβ) is one of the major, but as yet
elusive, goals in the treatment of Alzheimer's disease (AD). The amylin receptor, activated by …