Genetics of male infertility: from research to clinic
Male infertility is a multifactorial complex disease with highly heterogeneous phenotypic
representation and in at least 15% of cases, this condition is related to known genetic …
representation and in at least 15% of cases, this condition is related to known genetic …
Pathogenic landscape of idiopathic male infertility: new insight towards its regulatory networks
N Kothandaraman, A Agarwal, M Abu-Elmagd… - NPJ genomic …, 2016 - nature.com
Idiopathic male infertility (IMI) affects nearly 10− 15% of men in their prime reproductive age.
More than 500 target genes were postulated to be associated with this disease condition …
More than 500 target genes were postulated to be associated with this disease condition …
[HTML][HTML] Defining new genetic etiologies of male infertility: progress and future prospects
A Salas-Huetos, KI Aston - Translational Andrology and Urology, 2021 - ncbi.nlm.nih.gov
Male infertility is a common and complex disease, manifesting as a wide range of
phenotypes, ranging from apparently normal semen parameters with an inexplicable …
phenotypes, ranging from apparently normal semen parameters with an inexplicable …
Association between the CYP1A1 MspI polymorphism and risk of head and neck cancer: a meta-analysis
H Mohammadi, M Momeni Roochi, F Rezaei… - Scientific reports, 2022 - nature.com
The studies recommended the relationship between lots of polymorphisms with the head
and neck cancers (HNCs) risk. Herein, we reported the association between the CYP1A1 …
and neck cancers (HNCs) risk. Herein, we reported the association between the CYP1A1 …
Initiative for standardization of reporting genetics of male infertility
E Traven, A Ogrinc, T Kunej - Systems Biology in Reproductive …, 2017 - Taylor & Francis
The number of publications on research of male infertility is increasing. Technologies used
in research of male infertility generate complex results and various types of data that need to …
in research of male infertility generate complex results and various types of data that need to …
Interaction between β-hexachlorocyclohexane and ADIPOQ genotypes contributes to the risk of type 2 diabetes mellitus in East Chinese adults
S Li, X Wang, L Yang, S Yao, R Zhang, X Xiao… - Scientific Reports, 2016 - nature.com
Growing evidence links environmental exposure to hexachlorocyclohexanes (HCHs) to the
risk of type 2 diabetes mellitus (T2DM), and ADIPOQ that encodes adiponectin is considered …
risk of type 2 diabetes mellitus (T2DM), and ADIPOQ that encodes adiponectin is considered …
Disturbed testicular expression of the estrogen‐metabolizing enzymes CYP 1A1 and COMT in infertile men with primary spermatogenic failure: possible negative …
A Parada‐Bustamante, C Molina, C Valencia… - …, 2017 - Wiley Online Library
Estradiol (E2) is normally metabolized to hydroxyestradiols and methoxyestradiols by CYP
1A1, CYP 1B1 and COMT. However, an altered production of these metabolites by a …
1A1, CYP 1B1 and COMT. However, an altered production of these metabolites by a …
[HTML][HTML] TNF-α− 308 polymorphisms and male infertility risk: A meta-analysis and systematic review
T Mostafa, M Taymour - Journal of advanced research, 2016 - Elsevier
This study aimed to conduct a systematic review and meta-analysis of prospective studies
discussing TNF-α− 308 polymorphism and male infertility. This study was conformed to …
discussing TNF-α− 308 polymorphism and male infertility. This study was conformed to …
Potential Positive Association between Cytochrome P450 1A1 Gene Polymorphisms and Recurrent Pregnancy Loss: a Meta‐Analysis
J Li, Y Chen, S Mo, D Nai - Annals of Human Genetics, 2017 - Wiley Online Library
In order to discover the potential genetic risks associated with recurrent pregnancy loss
(RPL), this meta‐analysis was conducted to assess the association between CYP1A1 gene …
(RPL), this meta‐analysis was conducted to assess the association between CYP1A1 gene …
Association between CYP1A1 rs4646903 T> C genetic variations and male infertility risk: a meta-analysis
DH Cao, ZJ Ren, DL Lu, LR Liu, P Xu, Q Zhang, Q Wei - Medicine, 2019 - journals.lww.com
Background: Number of studies have been performed to investigate the relationship
between the CYP1A1 rs4646903 polymorphism and male infertility risk, but the sample size …
between the CYP1A1 rs4646903 polymorphism and male infertility risk, but the sample size …