Pathophysiology and therapeutic approaches for spinal cord injury
Spinal cord injury (SCI) is a disabling condition that disrupts motor, sensory, and autonomic
functions. Despite extensive research in the last decades, SCI continues to be a global …
functions. Despite extensive research in the last decades, SCI continues to be a global …
A comprehensive look at the psychoneuroimmunoendocrinology of spinal cord injury and its progression: mechanisms and clinical opportunities
MA Ortega, O Fraile-Martinez, C García-Montero… - Military Medical …, 2023 - Springer
Spinal cord injury (SCI) is a devastating and disabling medical condition generally caused
by a traumatic event (primary injury). This initial trauma is accompanied by a set of biological …
by a traumatic event (primary injury). This initial trauma is accompanied by a set of biological …
[HTML][HTML] Recent advances in nanomaterials for the treatment of spinal cord injury
W Gong, T Zhang, M Che, Y Wang, C He, L Liu, Z Lv… - Materials Today Bio, 2023 - Elsevier
Spinal cord injuries (SCIs) are devastating. In SCIs, a powerful traumatic force impacting the
spinal cord results in the permanent loss of nerve function below the injury level, leaving the …
spinal cord results in the permanent loss of nerve function below the injury level, leaving the …
[HTML][HTML] The neuroprotective effects of estrogen and estrogenic compounds in spinal cord injury
Spinal cord injury (SCI) occurs when the spinal cord is damaged from either a traumatic
event or disease. SCI is characterised by multiple injury phases that affect the transmission …
event or disease. SCI is characterised by multiple injury phases that affect the transmission …
Combination therapy using nanomaterials and stem cells to treat spinal cord injuries
As a part of the central nervous system, the spinal cord (SC) provides most of the
communications between the brain and other parts of the body. Any damage to SC interrupts …
communications between the brain and other parts of the body. Any damage to SC interrupts …
The NF-κB pathway: a focus on inflammatory responses in spinal cord injury
Y Ding, Q Chen - Molecular Neurobiology, 2023 - Springer
Spinal cord injury (SCI) is a type of central nervous system trauma that can lead to severe
nerve injury. Inflammatory reaction after injury is an important pathological process leading …
nerve injury. Inflammatory reaction after injury is an important pathological process leading …
Nanotherapeutics for Alleviating Anesthesia‐Associated Complications
B Lu, L Wei, G Shi, J Du - Advanced Science, 2024 - Wiley Online Library
Current management of anesthesia‐associated complications falls short in terms of both
efficacy and safety. Nanomaterials with versatile properties and unique nano‐bio …
efficacy and safety. Nanomaterials with versatile properties and unique nano‐bio …
Inhibition of calpain attenuates degeneration of substantia nigra neurons in the rotenone rat model of Parkinson's disease
V Zaman, KP Drasites, A Myatich, R Shams… - International Journal of …, 2022 - mdpi.com
In the central nervous system (CNS), calcium homeostasis is a critical determinant of
neuronal survival. Calpain, a calcium-dependent neutral protease, is widely expressed in …
neuronal survival. Calpain, a calcium-dependent neutral protease, is widely expressed in …
Targeted therapy of spinal cord injury: inhibition of apoptosis is a promising therapeutic strategy
W He, Z Li, H Gu, Q Pan, F Lin - Molecular Neurobiology, 2023 - Springer
Spinal cord injury (SCI) is a serious disabling central nervous system injury that can lead to
motor, sensory, and autonomic dysfunction below the injury level. SCI can be divided into …
motor, sensory, and autonomic dysfunction below the injury level. SCI can be divided into …
Pharmacological interventions targeting the microcirculation following traumatic spinal cord injury
R Wang, J Bai - Neural Regeneration Research, 2024 - journals.lww.com
Traumatic spinal cord injury is a devastating disorder characterized by sensory, motor, and
autonomic dysfunction that severely compromises an individual's ability to perform activities …
autonomic dysfunction that severely compromises an individual's ability to perform activities …