Update on baculovirus as an expression and/or delivery vehicle for vaccine antigens
SY Lin, YC Chung, YC Hu - Expert review of vaccines, 2014 - Taylor & Francis
After three decades of development, the baculovirus/insect cell expression system is now
recognized as a powerful platform for recombinant protein production. With a number of …
recognized as a powerful platform for recombinant protein production. With a number of …
A recombinant rabies vaccine expressing the trimeric form of the glycoprotein confers enhanced immunogenicity and protection in outbred mice
P Koraka, BJ Bosch, M Cox, R Chubet… - Vaccine, 2014 - Elsevier
Rabies is a disease characterized by an invariably lethal encephalitis of viral origin that can
be controlled by preventive vaccination programs of wildlife, domestic animals and humans …
be controlled by preventive vaccination programs of wildlife, domestic animals and humans …
Vaccine and adjuvant design for emerging viruses: mutations, deletions, segments and signaling
GC Bowick, AJ McAuley - Bioengineered bugs, 2011 - Taylor & Francis
Vaccination is currently the most effective strategy to medically control viral diseases.
However, developing vaccines is a long and expensive process, and traditional methods …
However, developing vaccines is a long and expensive process, and traditional methods …
Expression and solubilization of insect cell-based rabies virus glycoprotein and assessment of its immunogenicity and protective efficacy in mice
R Ramya, B Mohana Subramanian… - Clinical and Vaccine …, 2011 - Am Soc Microbiol
Rabies is a fatal zoonotic disease of serious public health and economic significance
worldwide. The rabies virus glycoprotein (RVG) has been the major target for subunit …
worldwide. The rabies virus glycoprotein (RVG) has been the major target for subunit …
Baculovirus transduction in mammalian cells is affected by the production of type I and III interferons, which is mediated mainly by the cGAS-STING pathway
S Amalfi, GN Molina, RJ Bevacqua, MG López… - Journal of …, 2020 - Am Soc Microbiol
The baculovirus Autographa californica multiple nucleopolyhedrovirus is an insect virus with
a circular double-stranded DNA genome, which, among other multiple biotechnological …
a circular double-stranded DNA genome, which, among other multiple biotechnological …
Rabies-virus-glycoprotein-pseudotyped recombinant baculovirus vaccine confers complete protection against lethal rabies virus challenge in a mouse model
Rabies virus has been an ongoing threat to humans and animals. Here, we developed a
new strategy to generate a rabies virus vaccine based on a pseudotyped baculovirus. The …
new strategy to generate a rabies virus vaccine based on a pseudotyped baculovirus. The …
Addition of C3d-P28 adjuvant to a rabies DNA vaccine encoding the G5 linear epitope enhances the humoral immune response and confers protection
G Galvez-Romero, M Salas-Rojas, EN Pompa-Mera… - Vaccine, 2018 - Elsevier
Rabies DNA vaccines based on full-length glycoprotein (G) induce virus neutralizing
antibody (VNA) responses and protect against the virus challenge. Although conformational …
antibody (VNA) responses and protect against the virus challenge. Although conformational …
[PDF][PDF] Engineering, production, and immunogenicity studies of a truncated form of rabies virus glycoprotein produced in Nicotiana benthamiana plant
G Mammadova, I Gurbuzaslan, G Nilufer, D Yuksel… - Med Sci, 2022 - researchgate.net
Rabies is a viral disease caused by the rabies virus (Lyssavirus) that affects the central
nervous system, ultimately leading to death and brain disease. Rabies usually transmitted …
nervous system, ultimately leading to death and brain disease. Rabies usually transmitted …
Induction of antigen-specific immune responses in mice by recombinant baculovirus expressing premembrane and envelope proteins of West Nile virus
B Zhu, J Ye, P Lu, R Jiang, X Yang, ZF Fu, H Chen… - Virology journal, 2012 - Springer
Abstract Background West Nile Virus (WNV) is an emerging arthropod-born flavivirus with
increasing distribution worldwide that is responsible for a large proportion of viral …
increasing distribution worldwide that is responsible for a large proportion of viral …
Baculovirus mediated transduction: analysis of vesicular stomatitis virus glycoprotein pseudotyping
SM Kolangath, SH Basagoudanavar, M Hosamani… - Virusdisease, 2014 - Springer
The recombinant baculoviruses were constructed to investigate the necessity of VSV-G
pseudotyping for mammalian cell transduction. The viruses were designed to express green …
pseudotyping for mammalian cell transduction. The viruses were designed to express green …