Method of determining the nucleotide sequence of oligonucleotides and DNA molecules

P Williams, TJ Taylor, DJB Williams, I Gould… - US Patent …, 2010 - Google Patents
The present invention relates to a novel method for analyzing nucleic acid sequences based
on real-time detection of DNA poly-merase-catalyzed incorporation of each of the four …

Methods and products for analyzing polymers

EY Chan - US Patent 8,168,380, 2012 - Google Patents
US8168380B2 - Methods and products for analyzing polymers - Google Patents
US8168380B2 - Methods and products for analyzing polymers - Google Patents Methods and …

Single molecule sequencing of captured nucleic acids

S Lapidus - US Patent 7,666,593, 2010 - Google Patents
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Stabilizing a nucleic acid for nucleic acid sequencing

PR Buzby - US Patent 7,220,549, 2007 - Google Patents
The invention provides methods for sequencing a nucleic acid comprising stabilizing a
primer/target nucleic acid duplex on a substrate. Methods of the invention generally …

Methods for identifying nucleic acid modifications

B Flusberg, J Korlach, J Wegener, TA Clark… - US Patent …, 2015 - Google Patents
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Methods and kits for analyzing polynucleotide sequences

S Quake - US Patent 7,981,604, 2011 - Google Patents
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AND HUMAN SERVICES (DHHS), US GOVERNMENT reassignment NATIONAL …

Methods and compositions for improving fidelity in a nucleic acid synthesis reaction

PR Buzby - US Patent 7,482,120, 2009 - Google Patents
The invention provides methods and compositions for improving the fidelity of a sequencing-
by-synthesis reaction by using a nucleotide derivative that forms a hydrogen bond with a …

Methods and apparatuses for analyzing polynucleotide sequences

SR Quake - US Patent 7,462,449, 2008 - Google Patents
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Patents US7462449B2 - Methods and apparatuses for analyzing polynucleotide sequences …

Methods for identifying nucleic acid modifications

B Flusberg, S Turner, J Lee, L Jia, J Korlach… - US Patent …, 2015 - Google Patents
Methods, compositions, and systems are provided for characterization of modified nucleic
acids. In certain preferred embodiments, single molecule sequencing methods are provided …

Methods and devices for nucleic acid sequence determination

T Harris, PR Buzby, M Jarosz, JJ Dimeo… - US Patent 7,635,562, 2009 - Google Patents
US7635562B2 - Methods and devices for nucleic acid sequence determination - Google
Patents US7635562B2 - Methods and devices for nucleic acid sequence determination …