[HTML][HTML] Biodegradable polymeric nanoparticles for drug delivery to solid tumors

A Gagliardi, E Giuliano, E Venkateswararao… - Frontiers in …, 2021 - frontiersin.org
Advances in nanotechnology have favored the development of novel colloidal formulations
able to modulate the pharmacological and biopharmaceutical properties of drugs. The …

Pharmaceutical assessment of polyvinylpyrrolidone (PVP): As excipient from conventional to controlled delivery systems with a spotlight on COVID-19 inhibition

M Kurakula, GSNK Rao - Journal of drug delivery science and technology, 2020 - Elsevier
Polyvinylpyrrolidone (PVP) is a water-soluble polymer obtained by polymerization of
monomer N-vinylpyrrolidone. PVP is an inert, non-toxic, temperature-resistant, pH-stable …

Stimuli-responsive In situ gelling system for nose-to-brain drug delivery

M Agrawal, S Saraf, S Saraf, SK Dubey, A Puri… - Journal of Controlled …, 2020 - Elsevier
The diagnosis and treatment of neurological ailments always remain an utmost challenge for
research fraternity due to the presence of BBB. The intranasal route appeared as an …

[HTML][HTML] Nanotherapeutics for nose-to-brain drug delivery: an approach to bypass the blood brain barrier

D Lee, T Minko - Pharmaceutics, 2021 - mdpi.com
Treatment of neurodegenerative diseases or other central nervous system (CNS) disorders
has always been a significant challenge. The nature of the blood-brain barrier (BBB) limits …

Chitosan-poly (lactide-co-glycolide)/poloxamer mixed micelles as a mucoadhesive thermo-responsive moxifloxacin eye drop to improve treatment efficacy in bacterial …

S Ch, SG Padaga, B Ghosh, S Roy, S Biswas - Carbohydrate polymers, 2023 - Elsevier
A mucoadhesive self-assembling polymeric system was developed to carry moxifloxacin (M)
for treating bacterial keratitis (BK). Chitosan-PLGA (C) conjugate was synthesized, and …

Stem Cell‐Niche Engineering via Multifunctional Hydrogel Potentiates Stem Cell Therapies for Inflammatory Bone Loss

G Li, Z Li, L Li, S Liu, P Wu, M Zhou, C Li… - Advanced Functional …, 2023 - Wiley Online Library
Effective therapies capable of simultaneously inhibiting inflammation and promoting bone
healing remain to be developed for inflammatory bone disease. Stem cell therapies hold …

[HTML][HTML] Curcumin-loaded mesoporous silica nanoparticles dispersed in thermo-responsive hydrogel as potential Alzheimer disease therapy

TC Ribeiro, RM Sábio, MT Luiz, LC de Souza… - Pharmaceutics, 2022 - mdpi.com
Alzheimer's disease (AD) is a neurodegenerative disorder characterized by cognitive and
behavioral impairment. Curcumin-loaded mesoporous silica nanoparticles (MSN-CCM) can …

[HTML][HTML] Smart stimuli-responsive hydrogels for drug delivery in periodontitis treatment

Y Wang, J Li, M Tang, C Peng, G Wang, J Wang… - Biomedicine & …, 2023 - Elsevier
Periodontitis is a chronic inflammatory disease initiated by pathogenic biofilms and host
immunity that damages tooth-supporting tissues, including the gingiva, periodontal ligament …

[HTML][HTML] Nose-to-brain delivery of therapeutic peptides as nasal aerosols

W Alabsi, BB Eedara, D Encinas-Basurto, R Polt… - Pharmaceutics, 2022 - mdpi.com
Central nervous system (CNS) disorders, such as psychiatric disorders, neurodegeneration,
chronic pain, stroke, brain tumor, spinal cord injury, and many other CNS diseases, would …

[HTML][HTML] Quercetin loaded cationic solid lipid nanoparticles in a mucoadhesive in situ gel—a novel intravesical therapy tackling bladder cancer

S Shawky, S Makled, A Awaad, N Boraie - Pharmaceutics, 2022 - mdpi.com
The study aim was to develop an intravesical delivery system of quercetin for bladder cancer
management in order to improve drug efficacy, attain a controlled release profile and extend …