The blood–brain barrier: structure, regulation, and drug delivery
Blood–brain barrier (BBB) is a natural protective membrane that prevents central nervous
system (CNS) from toxins and pathogens in blood. However, the presence of BBB …
system (CNS) from toxins and pathogens in blood. However, the presence of BBB …
Differential roles of regulatory T cells in Alzheimer's disease
A Jafarzadeh, A Sheikhi, Z Jafarzadeh, M Nemati - Cellular immunology, 2023 - Elsevier
Regulatory T (Treg) cells interact with a variety of resident cells and infiltrated immune cells
in the central nervous system (CNS) to modulate neuroinflammation and …
in the central nervous system (CNS) to modulate neuroinflammation and …
[HTML][HTML] Effect of dexmedetomidine on postoperative cognitive dysfunction and the T helper 17/regulatory T cell balance in geriatric patients undergoing orthopedic …
W Zhao, J Li, J Wang, M Liu, D Yu - American Journal of …, 2023 - ncbi.nlm.nih.gov
Objectives: To investigate the effect of dexmedetomidine (DEX) on alleviating postoperative
cognitive dysfunction (POCD) and T helper 17 (Th17)/regulatory T cell (Treg) imbalance in …
cognitive dysfunction (POCD) and T helper 17 (Th17)/regulatory T cell (Treg) imbalance in …
Protective role of IL-17-producing γδ T cells in a laser-induced choroidal neovascularization mouse model
YH Chang, CH Hsing, CJ Chiu, YR Wu, SM Hsu… - Journal of …, 2023 - Springer
Background Vision loss in patients with wet/exudative age-related macular degeneration
(AMD) is associated with choroidal neovascularization (CNV), and AMD is the leading cause …
(AMD) is associated with choroidal neovascularization (CNV), and AMD is the leading cause …
Advances in understanding glaucoma pathogenesis: A multifaceted molecular approach for clinician scientists
Glaucoma, a leading cause of irreversible blindness worldwide, is a spectrum of
neurodegenerative diseases characterized by the gradual deterioration of retinal ganglion …
neurodegenerative diseases characterized by the gradual deterioration of retinal ganglion …
Comparative evaluation of antioxidant activity, total phenolic content, anti-inflammatory, and antibacterial potential of Euphorbia-derived functional products
R Benjamaa, H Elbouny, H Errati, A Moujanni… - Frontiers in …, 2024 - frontiersin.org
This study assessed the medicinal properties of Euphorbia resinifera O. Berg (E. resinifera)
and Euphorbia officinarum subsp echinus (Hook. f. and Coss.) Vindt (Euphorbia echinus …
and Euphorbia officinarum subsp echinus (Hook. f. and Coss.) Vindt (Euphorbia echinus …
[HTML][HTML] Crosstalk between hypoxic cellular micro-environment and the immune system: a potential therapeutic target for infectious diseases
There are overwhelming reports on the promotional effect of hypoxia on the malignant
behavior of various forms of cancer cells. This has been proposed and tested exhaustively in …
behavior of various forms of cancer cells. This has been proposed and tested exhaustively in …
Inflammation as common link to progressive neurological diseases
Life expectancy has increased immensely over the past decades, bringing new challenges
to the health systems as advanced age increases the predisposition for many diseases. One …
to the health systems as advanced age increases the predisposition for many diseases. One …
Plasma soluble ST2 levels are higher in neurodegenerative disorders and associated with poorer cognition
YJ Tan, I Siow, SE Saffari, SKS Ting… - Journal of …, 2023 - content.iospress.com
Background: Suppressor of tumorgenicity 2 (ST2) is highly expressed in brain tissue and is a
receptor for interleukin 33 (IL-33). ST2 exists in two forms, a transmembrane receptor (ST2L) …
receptor for interleukin 33 (IL-33). ST2 exists in two forms, a transmembrane receptor (ST2L) …
Engineered biological nanoparticles as nanotherapeutics for tumor immunomodulation
JN Rahmat, J Liu, T Chen, ZH Li, Y Zhang - Chemical Society Reviews, 2024 - pubs.rsc.org
Biological nanoparticles, or bionanoparticles, are small molecules manufactured in living
systems with complex production and assembly machinery. The products of the assembly …
systems with complex production and assembly machinery. The products of the assembly …