Black Seed (Nigella sativa): A Favourable Alternative Therapy for Inflammatory and Immune System Disorders

OO Ojueromi, G Oboh, AO Ademosun - Inflammopharmacology, 2022 - Springer
In the recent years, various food additives, medicinal plants, and their bioactive components
have been utilized in anti-inflammatory and immunomodulatory therapy. Nigella sativa is a …

[HTML][HTML] Identification of SARS-CoV-2 RNA-dependent RNA polymerase inhibitors from the major phytochemicals of Nigella sativa: An in silico approach

SA Mir, A Firoz, M Alaidarous, B Alshehri… - Saudi Journal of …, 2022 - Elsevier
Abstract The coronavirus disease 2019 (COVID-19), which emerged in December 2019,
continues to be a serious health concern worldwide. There is an urgent need to develop …

[HTML][HTML] A phase I clinical trial to evaluate the safety of thymoquinone-rich black cumin oil (BlaQmax®) on healthy subjects: Randomized, double-blinded, placebo …

JV Thomas, ME Mohan, P Prabhakaran, B Maliakel… - Toxicology Reports, 2022 - Elsevier
Black cumin or black seed (Nigella sativa L.) is a popular medicinal herb and culinary spice
belonging to Ranunculacea family. Thymoquinone (TQ) is the major active phytoconstituent …

[HTML][HTML] Clinical and experimental effects of Nigella sativa and its constituents on respiratory and allergic disorders

Z Gholamnezhad, F Shakeri, S Saadat… - Avicenna journal of …, 2019 - ncbi.nlm.nih.gov
Objective: Black cumin or Nigella sativa (N. sativa) seed has been widely used traditionally
as a medicinal natural product because of its therapeutic effects. In this review, the medicinal …

[HTML][HTML] Potential Pharmacological Applications of Nigella Seeds with a Focus on Nigella sativa and Its Constituents against Chronic Inflammatory Diseases …

S Wahab, A Alsayari - Plants, 2023 - mdpi.com
The leading cause of death worldwide has been identified as chronic illnesses, according to
the World Health Organization (WHO). Chronic inflammatory conditions such as asthma …

[HTML][HTML] Comparative Immunomodulatory Activity of Nigella sativa L. Preparations on Proinflammatory Mediators: A Focus on Asthma

AE Koshak, NM Yousif, BL Fiebich… - Frontiers in …, 2018 - frontiersin.org
Introduction: A range of traditional and commercial preparations of NS is frequently used in
the treatment of several inflammatory diseases. Often, these preparations have poor …

Effect of saffron, black seed, and their main constituents on inflammatory cytokine response (mainly TNF-α) and oxidative stress status: An aspect on pharmacological …

Z Vafaeipour, M Ghasemzadeh Rahbardar… - Naunyn-Schmiedeberg's …, 2023 - Springer
Tumor necrosis factor-α (TNF-α), an inflammatory cytokine, is produced by monocytes and
macrophages. It is known as a'double-edged sword'because it is responsible for …

[HTML][HTML] A qualitative and quantitative comparison of Crocus sativus and Nigella sativa immunomodulatory effects

MR Khazdair, Z Gholamnezhad, R Rezaee… - Biomedicine & …, 2021 - Elsevier
The present article reviews and compares the immunomodulatory activities of Crocus
sativus (C. sativus) and Nigella sativa (N. sativa) and their main bioactive compounds …

The effects of Nigella sativa on respiratory, allergic and immunologic disorders, evidence from experimental and clinical studies, a comprehensive and updated …

S Saadat, MR Aslani, V Ghorani… - Phytotherapy …, 2021 - Wiley Online Library
Nigella sativa (N. sativa) seed had been used traditionally due to several pharmacological
effects. The updated experimental and clinical effects of N. sativa and its constituents on …

[HTML][HTML] The Role of Bioactive Compounds of Nigella sativa in Rheumatoid Arthritis Therapy—Current Reports

M Zielińska, K Dereń, E Polak-Szczybyło, AE Stępień - Nutrients, 2021 - mdpi.com
Black cumin (Nigella sativa, NS) is included in the Ranunculaceae family and is classified as
a medicinal plant due to very high levels of various bioactive compounds. They determine its …