The recommendations listed in this document are, whenever possible, evidence based. An
extensive review was conducted on literature published through November 2012, and other …

Paravalvular leak (PVL) is an uncommon yet serious complication associated with surgical
prosthetic valve implantation. Paravalvular leak can have significant clinical consequence …

Methods and devices for assessing the operation of a replacement heart valve. The method
includes endovascularly delivering a replacement heart valve to a vicinity of a heart valve in …

A prosthetic heart valve is provided with a cuff having features which promote sealing with
the native tissues even where the native tissues are irregular. The cuff may include a portion …

The present invention provides methods and apparatus for endovascularly replacing a
patient's heart valve. The appa ratus includes a replacement valve and an anchor having an …

Objectives: The purpose of this study was to evaluate the feasibility and efficacy of the
percutaneous device closure of a consecutive series of patients with periprosthetic …

The present invention relates to apparatus and methods for performing valvuloplasty. In
some embodiments, the apparatus includes an expandable braid valvuloplasty device. In …

A method for percutaneously replacing a heart valve of a patient. In some embodiments the
method includes the steps of percutaneously delivering a replacement valve and an …

Background—Percutaneous repair has emerged as a potential therapy for patients with
prosthetic paravalvular regurgitation. However, there is a relative paucity of data on the …

Paravalvular regurgitation affects 5% to 17% of all surgically implanted prosthetic heart
valves. Patients who have paravalvular regurgitation can be asymptomatic or present with …