Hypoxia-inducible factors and the regulation of lipid metabolism

I Mylonis, G Simos, E Paraskeva - Cells, 2019 - mdpi.com
Oxygen deprivation or hypoxia characterizes a number of serious pathological conditions
and elicits a number of adaptive changes that are mainly mediated at the transcriptional …

Regulation of glucose and lipid metabolism in health and disease

L Chen, XW Chen, X Huang, BL Song, Y Wang… - Science China life …, 2019 - Springer
Glucose and fatty acids are the major sources of energy for human body. Cholesterol, the
most abundant sterol in mammals, is a key component of cell membranes although it does …

The regulation of hepatic fatty acid synthesis and partitioning: the effect of nutritional state

L Hodson, PJ Gunn - Nature Reviews Endocrinology, 2019 - nature.com
Nonalcoholic fatty liver disease (NAFLD) is an increasing global public health burden.
NAFLD is strongly associated with type 2 diabetes mellitus, obesity and cardiovascular …

[HTML][HTML] Mitochondria bound to lipid droplets: where mitochondrial dynamics regulate lipid storage and utilization

IY Benador, M Veliova, M Liesa, OS Shirihai - Cell metabolism, 2019 - cell.com
The isolation and biochemical characterization of lipid droplet (LD)-associated mitochondria
revealed the capacity of the cell to produce and maintain distinct mitochondrial populations …

Update and nomenclature proposal for mammalian lysophospholipid acyltransferases, which create membrane phospholipid diversity

WJ Valentine, K Yanagida, H Kawana, N Kono… - Journal of Biological …, 2022 - ASBMB
The diversity of glycerophospholipid species in cellular membranes is immense and affects
various biological functions. Glycerol-3-phosphate acyltransferases (GPATs) and …

A journey into the world of insect lipid metabolism

U Toprak, D Hegedus, C Doğan… - Archives of insect …, 2020 - Wiley Online Library
Lipid metabolism is fundamental to life. In insects, it is critical, during reproduction, flight,
starvation, and diapause. The coordination center for insect lipid metabolism is the fat body …

Triacylglycerol Metabolism in Drosophila melanogaster

C Heier, RP Kühnlein - Genetics, 2018 - academic.oup.com
Triacylglycerol (TAG) is the most important caloric source with respect to energy
homeostasis in animals. In addition to its evolutionarily conserved importance as an energy …

Host metabolism dysregulation and cell tropism identification in human airway and alveolar organoids upon SARS-CoV-2 infection

R Pei, J Feng, Y Zhang, H Sun, L Li, X Yang, J He… - Protein & …, 2021 - academic.oup.com
Abstract The coronavirus disease 2019 (COVID-19) pandemic is caused by infection with
the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which is spread …

[HTML][HTML] Lipo-nutritional quality of pork: The lipid composition, regulation, and molecular mechanisms of fatty acid deposition

W Yi, Q Huang, Y Wang, T Shan - Animal Nutrition, 2023 - Elsevier
Pork is one of the main meats consumed by people, and its nutritional value is closely
related to human health. The lipid deposition and composition of pork not only affect the …

Nuclear lipid droplets form in the inner nuclear membrane in a seipin-independent manner

K Sołtysik, Y Ohsaki, T Tatematsu, J Cheng… - Journal of Cell …, 2020 - rupress.org
Nuclear lipid droplets (LDs) in hepatocytes are derived from precursors of very-low-density
lipoprotein in the ER lumen, but it is not known how cells lacking the lipoprotein secretory …