Cardiovascular-kidney-metabolic health reflects the interplay among metabolic risk factors,
chronic kidney disease, and the cardiovascular system and has profound impacts on …

A growing appreciation of the pathophysiological interrelatedness of metabolic risk factors
such as obesity and diabetes, chronic kidney disease, and cardiovascular disease has led …

Importance Sodium-glucose cotransporter 2 inhibitors are known to reduce heart failure
events and slow progression of kidney disease among patients with heart failure and a …

Selenium (Se) is an essential element for maintaining human health. The biological effects
and toxicity of Se compounds in humans are related to their chemical forms and …

A significant proportion of patients experience delays in the diagnosis of heart failure due to
the non‐specific signs and symptoms of the syndrome. Diagnostic tools such as …

The correlation between obesity, type 2 diabetes mellitus (DM), cardiovascular disease
(CVD), and chronic kidney disease (CKD) is an escalating and widely acknowledged …

Protein phosphorylation is an important post‐transcriptional modification involving an
extremely wide range of intracellular signaling transduction pathways, making it an …

Rationale & Objective Chronic kidney disease (CKD) is associated with an increased risk of
cardiovascular (CV) mortality, but there are limited data on temporal trends disaggregated …

The syndrome of heart failure (HF) has historically been dichotomized based on clinical trial
inclusion criteria into patients with a reduced or preserved left ventricular ejection fraction …

Aim In this subgroup analysis of STRONG‐HF, we explored the association between
changes in renal function and efficacy of rapid up‐titration of guideline‐directed medical …