Biofilm-innate immune interface: contribution to chronic wound formation

Z Versey, WS da Cruz Nizer, E Russell, S Zigic… - Frontiers in …, 2021 - frontiersin.org
Delayed wound healing can cause significant issues for immobile and ageing individuals as
well as those living with co-morbid conditions such as diabetes, cardiovascular disease, and …

Chronic wounds: Treatment consensus

E Eriksson, PY Liu, GS Schultz… - Wound repair and …, 2022 - Wiley Online Library
Abstract The Wound Healing Foundation (WHF) recognised a need for an unbiased
consensus on the best treatment of chronic wounds. A panel of 13 experts were invited to a …

Microbial interplay in skin and chronic wounds

C Sachdeva, K Satyamoorthy, TS Murali - Current Clinical Microbiology …, 2022 - Springer
Abstract Purpose of Review Microbial infections in chronic wounds can often lead to lower-
limb amputation, decrease in quality of life, and increase in mortality rate, and there is an …

Prevalence and Predictors of Pseudomonas aeruginosa Among Hospitalized Patients With Diabetic Foot Infections

MP Veve, NJ Mercuro, RJ Sangiovanni… - Open forum …, 2022 - academic.oup.com
Abstract Background Diabetic foot infections (DFIs) are commonly associated with antibiotic
overuse. Empiric DFI treatment often includes coverage for Pseudomonas aeruginosa (PsA) …

Efficacy of a topical concentrated surfactant gel on microbial communities in non‐healing diabetic foot ulcers with chronic biofilm infections: a proof‐of‐concept study

M Malone, M Radzieta, S Schwarzer… - International Wound …, 2021 - Wiley Online Library
This proof‐of‐concept study sought to determine the effects of standard of care (SOC) and a
topically applied concentrated surfactant gel (SG) on the total microbial load, community …

Efficacy of surgical/wound washes against bacteria: Effect of different in vitro models

F Parvin, K Vickery, AK Deva, H Hu - Materials, 2022 - mdpi.com
Topical antiseptics are often used to treat chronic wounds with biofilm infections and during
salvage of biofilm contaminated implants, but their antibacterial efficacy is frequently only …

Nanopore 16S amplicon sequencing enhances the understanding of pathogens in medically intractable diabetic foot infections

J Moon, N Kim, HS Lee, ST Lee, KH Jung, KI Park… - Diabetes, 2021 - Am Diabetes Assoc
Diabetic foot infections (DFIs) cause substantial morbidity and mortality. The mainstay of the
treatment is empiric antibiotics and surgical debridement in severe cases. In this study, we …

Distinct microbiome profiles and biofilms in Leishmania donovani-driven cutaneous leishmaniasis wounds

TD Jayasena Kaluarachchi, PM Campbell… - Scientific reports, 2021 - nature.com
The endemic strain of Leishmania donovani in Sri Lanka causes cutaneous leishmaniasis
(CL) rather than more common visceral form. We have visualized biofilms and profiled the …

Update on prevalence and antimicrobial resistance of Staphylococcus aureus and Pseudomonas aeruginosa isolated from diabetic foot ulcers in Africa: a systematic …

D Makeri, M Odoki, E Eilu, E Agwu - Bulletin of the National Research …, 2023 - Springer
Background Diabetes mellitus is increasing in Africa, and diabetes-related amputations
exacerbated by diabetic foot infection are also prevalent with Staphylococcus aureus and …

Rapid microbiological diagnosis based on 16S rRNA gene sequencing: A comparison of bacterial composition in diabetic foot infections and contralateral intact skin

Y Huang, Z Xiao, Y Cao, F Gao, Y Fu, M Zou… - Frontiers in …, 2022 - frontiersin.org
Diabetic foot infections (DFIs) represent a frequent complication of diabetes and a major
cause of amputations. This study aimed to evaluate the utility of 16S rRNA gene sequencing …